33477-29-1

Upstream product

• 1161-13-3 N-Cbz-L-Phe 
• 21691-57-6 L-leucine p-nitrobenzyl ester 
• 75243-86-6 3-O--hydroxy-2-phenylindenone 
• 80633-17-6 Z-Phe-ONp-Pic * HOTs 

Downstream Products

• 75244-07-4 glycylglycyl-L-phenylalanyl-L-leucine p-nitrobenzyl ester hydrobromide 
• 75244-04-1 glycyl-L-phenylalanyl-L-leucine p-nitrobenzyl ester hydrobromide 
• 75244-05-2 benzyloxycarbonylglycylglycyl-L-phenylalanyl-L-leucine p-nitrobenzyl ester 
• 75244-03-0 benzyloxycarbonylglycyl-L-phenylalanyl-L-leucine p-nitrobenzyl ester 
• 75244-08-5 4-nitrobenzyl ester of N-benzyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine 
• 58822-25-6 Leu-enkephalin 
• 75244-01-8 L-phenylalanyl-L-leucine p-nitrobenzyl ester hydrobromide 

Relevant academic research and scientific papers

Protected Amino Acid Active Esters Incorporating the 4-Picolyl Basic Solubilizing Group

The 4-picolyl ester of 4-hydroxy-3-nitrophenylacetic acid has been prepared from an active polyester intermediate, and used as the precursor of a series of protected amino acid active esters.These compounds were satifactory coupling components in peptide syntheses.Purification of the protected peptides by acid washing was facilitated by the presence of the basic 4-picolyl moiety.

3-O--HYDROXY-2-PHENYLINDENONES, PREPARATION AND USE IN THE SYNTHESIS OF PEPTIDES

Several 3-O--hydroxy-2-phenylindenones were obtained and used in the synthesis of peptides.Synthesis of Leu-enkephalin was carried out.