334969-15-2Relevant academic research and scientific papers
Decarbonylation of Salicylaldehyde Activated by p-Cymene Ruthenium(II) Dimer: Implication for Catalytic Alkyne Hydrothiolation
Modem, Sarangapani,Kankala, Shravankumar,Balaboina, Ramesh,Thirukovela, Narasimha Swamy,Jonnalagadda, Sreekantha B.,Vadde, Ravinder,Vasam, Chandra Sekhar
, p. 4635 - 4642 (2016/09/28)
A stoichiometric C–H activation/decarbonylation of salicylaldehyde by [(η6-p-cymene)RuCl2]2gave a carbonyl derivative [(η6-p-cymene)RuCl(CO)(Ph-O)] (1) without the use of CO gas. A variety of polar phosphines were then incorporated into compound 1 to give new RuIIcationic catalysts, [(η6-p-cymene)Ru(CO)(Ph-O)L]BF4(2–8). These were used to catalyse the hydrothiolation of alkynes with a range of thiols in aqueous THF to give anti-Markovnikov E-linear vinyl sulfides in high yields.
One-pot synthesis of alkyl styryl sulfides free from transition metal/ligand catalyst and thiols
Heredia, Adrian A.,Penenory, Alicia B.
, p. 991 - 997 (2013/03/14)
A new protocol for the one-pot synthesis of styryl alkyl sulfides was developed. This methodology involves the in situ generation of thiolate anions by nucleophilic substitution between potassium thioacetate and alkyl halides followed by fragmentation. Further reactions of these thiolate anions with substituted (E,Z)-β-styryl halides gave the corresponding sulfides with retention of stereochemistry in good to excellent yields. This procedure does not require a metal catalyst, it proceeds under mild conditions and in short times, and it is free from malodorous and air-sensitive alkyl thiols. Copyright
Z-styryl sulfone anticancer agents
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, (2008/06/13)
(Z)-styryl benzylsulfones of formula I are useful as anticancer agents: wherein R1is selected from the group consisting of hydrogen, chloro and nitro; R2is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, ch
Z-styryl sulfone anticancer agents
-
, (2008/06/13)
(Z)-styryl benzylsulfones of formula I are useful as anticancer agents: wherein R1is selected from the group consisting of hydrogen, chloro and nitro; R2is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, ch
