335004-29-0

Upstream product

• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 70-55-3 toluene-4-sulfonamide 
• 335004-22-3 (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-methylphenyl)sulfonyl]-2-butene-1,4-diamine 

Downstream Products

• 335003-91-3 (E,E,E)-N,N'-bis[(4-methylphenyl)sulfonyl]-1,14-dibromo-5,10-diazatetradeca-2,7,12-triene 
• 945082-49-5 (E,E,E)-1,16-bis(tert-butyloxycarbonyl)-1,6,11,16-tetrakis[(4-methylphenyl)sulfonyl]-1,6,11,16-tetraazahexadeca-3,8,13-triene 
• 945082-78-0 (E,E,E,E,E)-1,26-bis(tert-butyloxycarbonyl)-1,6,11,16,21,26-hexakis[(4-methylphenyl)sulfonyl]-1,6,11,16,21,26-hexaazahexacosa-3,8,13,18,23-pentaene 
• 945082-62-2 (E,E,E)-1,6,11,16-tetrakis[(4-methylphenyl)sulfonyl]-1,6,11,16-tetraazahexadeca-3,8,13-triene 
• 949162-87-2 (E)-1-benzyloxy-5,10-bis(p-toluenesulfonyl)-5,10-diazatetradec-7-ene-2,12-diyne 

Relevant academic research and scientific papers

Highly Z-selective olefins metathesis

The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.

HIGHLY Z-SELECTIVE OLEFINS METATHESIS

The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.

Highly Z-selective metathesis homocoupling of terminal olefins

(Chemical Equation Presented) Mo and W MonoAryloxide-Pyrrolide (MAP) olefin metathesis catalysts can couple terminal olefins to give as high as >98% Z-products in moderate to high yields with as little as 0.2% catalyst. Results are reported for 1-hexene, 1-octene, allylbenzene, allyltrimethylsilane, methyl-10-undecenoate, methyl-9-decenoate, allylB(pinacolate), allylOBenzyl, allylNHTosyl, and allylNHPh. It is proposed that high Z-selectivity is achieved because a large aryloxide only allows metallacyclobutanes to form that contain adjacent cis substituents and because isomerization of Z-product to E-product can be slow in that same steric environment.

Preparation of nitrogen-containing 15-membered triolefinic macrocycles: (E,E,E)-1,6,11-tris(arylsulfonyl)-1,6,11-triazacyclopentadeca-3,8,13-trienes

Three routes to (E,E,E)-1,6,11-tris(arylsulfonyl)-1,6,11-triazacyclopentadeca-3,8,13-trienes are described. Optimization of the preparation of key intermediates has opened the way to efficient synthesis of a broad variety of 15-membered, nitrogen-containing triolefinic macrocycles.