33511-28-3Relevant academic research and scientific papers
On products of reaction of imidazole with benzoyl chloride under conditions of the Regel - Buchel reaction
Morkovnik,Khrustalev
, p. 1550 - 1552 (1998)
The reaction of imidazole with benzoyl chloride in pyridine afforded cis-1,2-bis(benzoylamino)ethylene (1) rather than 2-benzoylimidazole, as has been suggested previously. The structure of 1 was confirmed by 1H NMR spectroscopy and X-ray diffraction study.
One-pot domino synthesis of polyvicinalamine monomers
Kilic, Cem B.,Taralp, Alpay
experimental part, p. 506 - 510 (2011/06/22)
Imidazole was generated in situ via a domino reaction between glyoxal, formaldehyde, and two units of aqueous ammonia. Aqueous bicarbonate and a carboxylic anhydride or dialkyl dicarbonate were added, yielding the corresponding N, N′-diacyl or N,N′-dicarbalkoxy-2- hydroxyimidazoline. A Bamberger ring cleavage ensued, affording cis-1,2-di(acetamido)- ethene, cis-1,2-di(propylamido)ethene, cis-1,2-di(ethoxyamido)ethene, cis-1,2-di(tert-butoxyamido)ethene, or cis-1,2-di(benzamido) ethene as easily isolable solids. The convenience and generality offered by this one-pot approach implied a cost-effective route to the routine synthesis of oligo- and polyvicinalamine precursors.
