335117-49-2

Upstream product

• 335117-43-6 3-Phenethylsulfanyl-1-((S)-1-phenyl-ethyl)-pyrrolidine-2,5-dione 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 33139-84-3 (Z)-3-((S)-1-Phenyl-ethylcarbamoyl)-acrylic acid 
• 60925-76-0 (S)-(-)-α-Methylbenzylmaleimide 

Relevant academic research and scientific papers

Synthesis and reactivity of (1S)-N-(1-phenylethyl)maleimide towards nucleophiles: An application to preparation of chiral pyrroloisothiochroman and pyrrolobenzo[d]thiepine based on π-cationic cyclization

Chiral pyrroloisothiochroman and pyrrolo[d]thiepine were obtained efficiently in four steps from N-alkylated maleimides via, successively, sulfurization, regioselective reduction followed by π-cationic cyclization of the N-acyliminium ion intermediates. These latter, in addition, led to conjugate enamides as a consequences of the dehydration reaction.