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60925-76-0

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60925-76-0 Usage

General Description

(S)-(-)-N-(1-phenylethyl)maleimide is a chemical compound with the molecular formula C12H11NO2. It is a derivative of maleimide and features a phenylethyl group. (S)-(-)-N-(1-PHENYLETHYL)MALEIMIDE is commonly used in organic synthesis as a dienophile in Diels-Alder reactions and as a substrate in enzymatic reactions. It is also known for its applications as a reagent in the preparation of pharmaceuticals and agrochemicals. In addition, it has been utilized as a building block in the synthesis of various biologically active compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 60925-76-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,9,2 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60925-76:
(7*6)+(6*0)+(5*9)+(4*2)+(3*5)+(2*7)+(1*6)=130
130 % 10 = 0
So 60925-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO2/c1-9(10-5-3-2-4-6-10)13-11(14)7-8-12(13)15/h2-9H,1H3/t9-/m0/s1

60925-76-0 Well-known Company Product Price

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  • Aldrich

  • (461563)  (S)-(−)-N-(1-Phenylethyl)maleimide  97%

  • 60925-76-0

  • 461563-1G

  • 2,056.86CNY

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60925-76-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(1S)-1-phenylethyl]pyrrole-2,5-dione

1.2 Other means of identification

Product number -
Other names (S)-(-)-N-(1-feniletil)maleimide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60925-76-0 SDS

60925-76-0Relevant articles and documents

Maleimide-based metal-free ligation with dienes: A comparative study

Bailly, Laetitia,Frisby, Axel,Le Nahenec-Martel, Patricia,Lossouarn, Alexis,Renard, Pierre-Yves,Renault, Kévin,Sabot, Cyrille

, p. 3874 - 3887 (2020/06/03)

A brief literature survey reveals that metal-free ligation such as the maleimide-based cycloaddition with electron-rich (hetero)dienes is a widespread tool for the assembly of (bio)molecular systems with applications in biotechnology, materials science, polymers and bio-organic chemistry. Despite their everyday use, only scattered data about their kinetics as well as the stabilities of corresponding products under physiological conditions, are accessible. These key parameters are yet, of paramount importance to ensure the rapid and effective preparation of stable compounds. Herein is reported a systematic study regarding the different classes of dienes used in chemoselective ligation, including their accessibility and stability, as well as comparative kinetic experiments and products stability assays. We took advantage of these data to develop a double labeling strategy from the combined use of cyclopentadiene and oxazole dienes.

Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonists

Zhang, Hao,Ding, Charles Z.,Lai, Zhi,Chen, Sean S.,Devasthale, Pratik,Herpin, Tim,Morton, George,Qu, Fucheng,Ryono, Denis,Smirk, Rebecca,Wang, Wei,Wu, Shung,Ye, Xiang-Xang,Li, Yi-Xin,Apedo, Atsu,Farrelly, Dennis,Wang, Tao,Gu, Liqun,Morgan, Nathan,Flynn, Neil,Chu, Cuixia,Kunselman, Lori,Lippy, Jonathan,Locke, Kenneth,O'Malley, Kevin,Harrity, Thomas,Cap, Michael,Zhang, Lisa,Hosagrahara, Vinayak,Kadiyala, Pathanjali,Xu, Carrie,Doweyko, Arthur M.,Zahler, Robert,Hariharan, Narayanan,Cheng, Peter T.W.

, p. 1196 - 1205 (2015/04/27)

The design, synthesis and structure-activity relationships of a novel series of 3,4-disubstituted pyrrolidine acid analogs as PPAR ligands is outlined. In both the 1,3- and 1,4-oxybenzyl pyrrolidine acid series, the preferred stereochemistry was shown to be the cis-3R,4S isomer, as exemplified by the potent dual PPARα/γ agonists 3k and 4i. The N-4-trifluoromethyl-pyrimidinyl pyrrolidine acid analog 4i was efficacious in lowering fasting glucose and triglyceride levels in diabetic db/db mice.

Heat-resistant poly(N-(1-phenylethyl)maleimide-co-styrene) microspheres prepared by dispersion polymerization

Tong, Linyue,Cui, Xin,Yang, Wantai,Deng, Jianping

supporting information; experimental part, p. 6697 - 6703 (2012/08/08)

This article reports on a novel type of polymeric microsphere consisting of poly(N-(1-phenylethyl)maleimide-co-styrene) (poly(N-PEMI-co-St)) and showing remarkable heat resistance. Such microspheres were prepared by dispersion polymerization with 2,2′-azo

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