335164-35-7

Upstream product

• 154349-03-8 (E)-2-[4-(3-methoxy-3-oxoprop-1-en-1-yl)phenyl]acetic acid 
• 34841-47-9 2-(4-formylphenyl)acetic acid 
• 73401-74-8 4-hydroxymethylphenylacetic acid 

Downstream Products

• 156781-13-4 methyl 4-formylmethylcinnamate 
• 1018674-52-6 tert-butyl N-(2-{4-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]phenyl}ethyl)-L-leucinate 

Relevant academic research and scientific papers

HDAC INHIBITORS

Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent =C- or =N-; W is a divalent radical -CH=CH- or CH2CH2-; R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular carboxyesterase enzymes to a carboxylic acid group; R2 is the side chain of a natural or non-natural alpha amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.