335254-72-3Relevant academic research and scientific papers
PYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF
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Paragraph 0149-0150, (2019/02/13)
Provided are a pyrimidine compound represented by Formula 1, a method of preparing the same, and a pharmaceutical use of the pyrimidine compound for the prevention or treatment of cancer.
COMPOUNS, COMPOSITIONS AND METHODS OF USE
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Page/Page column 230, (2018/07/29)
Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.
4-(Benzoimidazol-2-yl)-thiazole Compounds and Related Aza Derivatives
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Paragraph 0850, (2015/01/06)
The invention relates to compounds of Formula (I) wherein ring A, X, (R1)n, R2, R3, R4, R4′, R5, n, and p are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as modulators of the CXCR3 receptor.
4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES
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Page/Page column 119, (2013/08/15)
The invention relates to compounds of Formula (I) wherein ring A, X, (R1)n, R2, R3, R4, R4', R5, n, and p are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as modulators of the CXCR3 receptor.
BENZIMIDAZOLE ANTIVIRAL AGENTS
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Page/Page column 79-80, (2011/09/14)
Provided are compounds of Formula (I) and (II) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).
SUBSTITUTED HYDANTOINS
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Page/Page column 13, (2009/03/07)
This invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are described in this application. These compounds inhibit the enzymes MEK 1 and MEK2, protein kinases that are components o
PYRAZOLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AND AUTOIMMUNE DISORDERS
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Page/Page column 25, (2008/06/13)
Compounds of formula (I) are inhibitors of PDK1 and CHK1 activity, and of use in the treatment of cancer and autoimmune disorders (I) : wherein R2 is a radical of formula R7-(CH2)n-, or a radical of formula -Alk
Glutamate receptor antagonists
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, (2008/06/13)
The present invention is a compound of formula wherein X is an ethynediyl group, R1, R2and R3are as defined in the specification.
