335266-02-9

Upstream product

• 620-08-6 4-methoxypyridine 
• 501-53-1 benzyl chloroformate 
• 185847-84-1 benzyl 4-oxo-3,4-dihydropyridine-1(2H)-carboxylate 
• 335265-99-1 2-ethenyl-3,4-dihydro-4-oxo-1(2H)-pyridinecarboxylic acid phenylmethyl ester 

Relevant academic research and scientific papers

Copper-catalyzed asymmetric 1,4-addition of alkenyl alanes to N-substituted-2-3-dehydro-4-piperidones

Readily available vinyl alanes are used in the Cu-catalyzed asymmetric conjugate addition reaction to N-substituted-2-3-dehydro-4-piperidones. The enhanced reactivity of recently developed and easily prepared phosphine amine ligands in combination with inexpensive Cu(II)naphtenate (CuNp) allows the introduction of a great variety of alkenyl, alkyl, and aryl aluminums in high enantioselectivity.