335275-93-9

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 53312-81-5 3-cyano-4-fluoroaniline 
• 407-25-0 trifluoroacetic anhydride 
• 161886-21-1 2-fluoro-5-hydrazinobenzonitrile 

Downstream Products

• 545444-98-2 2,2,2-trifluoro-N-(3-cyano-4-fluoro)phenylethanehydrazonoyl mesylate 
• 545445-03-2 2,2,2-trifluoro-N-(3-cyano-4-fluoro)phenylethanehydrazonoyl chloride 
• 545445-01-0 2,2,2-trifluoro-N-(3-cyano-4-fluoro)phenylethanehydrazonoyl benzenesulfonate 
• 335275-94-0 2,2,2-trifluoro-N-(3-cyano-4-fluoro)phenylethanehydrazonoyl tosylate 

Relevant academic research and scientific papers

Process for the preparation of 1,3,5-trisubstituted pyrazoles via [3+2] cycloaddition

A process for the preparation of 1,3,5-trisubstituted pyrazole compounds, which are useful intermediates in the synthesis of factor Xa inhibitors.

Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones

A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds are useful as factor Xa inhibitors.

Synthesis of 1,3,5-trisubstituted pyrazoles

A novel process for making 1,3,5-trisubstituted pyrazoles of the type shown below from appropriate phenyl hydrazines is described. These compounds are useful as factor Xa inhibitors.