335282-32-1Relevant academic research and scientific papers
Synthesis and evaluation of 7-chloro-4-(piperazin-1-yl)quinoline- sulfonamide as hybrid antiprotozoal agents
Salahuddin, Attar,Inam, Afreen,Van Zyl, Robyn L.,Heslop, Donovan C.,Chen, Chien-Teng,Avecilla, Fernando,Agarwal, Subhash M.,Azam, Amir
, p. 3080 - 3089 (2013)
A new series of 4-aminochloroquinoline based sulfonamides were synthesized and evaluated for antiamoebic and antimalarial activities. Out of the eleven compounds evaluated (F1-F11), two of them (F3 and F10) showed good activity against Entamoeba histolyti
ACTIVATORS OF CYLINDRICAL PROTEASES
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Page/Page column 56, (2012/06/30)
The present invention is directed to activators of cylindrical proteases ("ACPs"), particularly ClpP, and the role thereof in the diagnosis and treatment of bacterial infections. A number of ACPs were identified that activate caseinolytic protease P ("Clp
