33534-88-2

Basic information

• Product Name: Propanedinitrile, (4-methylphenyl)-
• CAS NO: 33534-88-2
• Molecular Formula: C10H8N2
• Molecular Weight: 156.187
• Mol File: 33534-88-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Propanedinitrile, (4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedinitrile, (4-methylphenyl)-(33534-88-2)
• EPA Substance Registry System: Propanedinitrile, (4-methylphenyl)-(33534-88-2)

Safety Data

• Hazardous Substances Data: 33534-88-2(Hazardous Substances Data)

Upstream product

• 99779-70-1 2-Chloro-2-p-tolyl-malononitrile 
• 30698-31-8 methyl 2-cyano-2-(p-tolyl) acetate 
• 30698-52-3 2-cyano-2-(p-tolyl) acetamide 
• 106-43-4 para-chlorotoluene 
• 131211-27-3 di-1-adamantylphosphine 
• 4341-85-9 malonitrile 
• 106-38-7 para-bromotoluene 
• 865-48-5 sodium t-butanolate 
• 86866-05-9 2-p-Tolyl-2-trimethylsilanyloxy-malononitrile 
• 874-60-2 4-methyl-benzoyl chloride 
• 109-77-3 malononitrile 
• 624-31-7 4-tolyl iodide 
• 91880-02-3 (1,2,3-trimethylcyclopropenyl)(p-methylphenyl)malononitrile 
• 2947-61-7 (4-methylphenyl)acetonitrile 

Downstream Products

• 37449-71-1 4-methyl-α,α-dicyanobenzyl radical 
• 1393345-90-8 4-(p-tolyl)-1H-pyrazole-3,5-diamine 
• 91880-02-3 (1,2,3-trimethylcyclopropenyl)(p-methylphenyl)malononitrile 
• 14271-73-9 4-methylbenzoyl cyanide 

Relevant articles and documents

Preparation of O-Protected Cyanohydrins by Aerobic Oxidation of α-Substituted Malononitriles in the Presence of Diarylphosphine Oxides

A mild, reagent-cyanide-free, and efficient synthesis of O-phosphinoyl-protected cyanohydrins from readily available α-substituted malononitriles was realized using diarylphosphine oxides in the presence of O2. Mechanistic studies indicated that in addition to the initial aerobic oxidation of the malononitrile derivative notable features of this process include the formation of a tetrahedral intermediate and a subsequent intramolecular rearrangement. The phosphinoyl-protecting group can be removed by alcoholysis or by reduction with DIBAL-H.

Synthesis of substituted isoquinolines via Pd-catalyzed cross-coupling approaches

Palladium complexes incorporating ligands based on a 1,3,5,7-tetramethyl-2, 4,8-trioxa-6-phosphaadamantanyl scaffold were used to catalyze the arylation of ethyl cyanoacetate, malononitrile, and various ketones. The products from these reactions can be el

PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES

Phenylmalonic acid dinitriles are prepared by reaction of, for example, phenyl Kalides with malonic acid dinitrile in the presence of palladium catalysts and bases.