335350-55-5

Upstream product

• 335349-98-9 (5-hydroxymethyl-4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester 
• 536-74-3 phenylacetylene 
• 473547-14-7 (5-dimethylamino-4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester 

Downstream Products

• 335350-90-8 2,2-dimethyl-propionic acid 4-amino-5-tert.-butoxycarbonylamino-2-phenylethynyl-benzyl ester 
• 335350-88-4 (2-amino-5-ethoxymethyl-4-phenylethynyl-phenyl)-carbamic acid tert.-butyl ester 

Relevant academic research and scientific papers

Dihydro-benzo [b][1,4]diazepin-2-one derivatives

This invention is a dihydro-benzo[b][1,4]diazepin-2-one derivative of the formula wherein R1, R2, R3, X and Y are as defined in the specification. The invention includes pharmaceutical compositions containing these compounds, a process for their preparation, their use in preparation of pharmaceutical compositions and administration of an effective amount of the compounds for the treatment or prevention of acute and/or chronic neurological disorders to a patient in need of such treatment.

Glutamate receptor antagonists

The present invention relates to compounds of with a base structure of formula 1 The compounds of formula I are shown to have activity as metabotropic glutamate receptor antagonists.