33543-54-3Relevant academic research and scientific papers
Electrophilic N-amination of two quinazoline-2,4-diones using substituted (Nitrophenyl)hydroxylamines
Boyles, David C.,Curran, Timothy T.,Parlett IV, Roger V.,Davis, Mark,Mauro, Frank
, p. 230 - 233 (2002)
The preparation of a few (nitrophenyl)hydroxylamines and reaction with two quinazoline-2,4-diones is described. The electrophilic aminating agents were assessed in terms of yield for the N-amination of two quinazoline-2,4-diones and safety considerations for rapid scale-up. For the amination of the described system, the best yield and the highest onset temperature were found in the same aminating agent, specifically, (4-nitrophenyl)hydroxylamine.
PENAM DERIVATIVES FOR TREATING BACTERIAL INFECTIONS
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Paragraph 0015; 0374, (2021/03/13)
Novel iron chelating group conjugated penam derivatives described herein show antibacterial activity, and could be used as antibacterial agents or beta-lactamase inhibitors (BLIs) which are of value for application in combination with other antibacterial
