33544-42-2

Basic information

• Product Name: 4-HYDRAZINO-3-NITROPYRIDINE
• Synonyms: PYRIDINE, 4-HYDRAZINO-3-NITRO-;4-HYDRAZINO-3-NITROPYRIDINE;(3-nitropyridin-4-yl)hydrazine
• CAS NO: 33544-42-2
• Molecular Formula: C₅H₆N₄O₂
• Molecular Weight: 154.13
• EINECS: 125-856-9
• Mol File: 33544-42-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 200 °C
• Boiling Point: 341 °C at 760 mmHg
• Flash Point: 160 °C
• Appearance: /
• Density: 1.524 g/cm³
• Vapor Pressure: 8.28E-05mmHg at 25°C
• Refractive Index: 1.707
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 4.17±0.36(Predicted)
• CAS DataBase Reference: 4-HYDRAZINO-3-NITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDRAZINO-3-NITROPYRIDINE(33544-42-2)
• EPA Substance Registry System: 4-HYDRAZINO-3-NITROPYRIDINE(33544-42-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 33544-42-2(Hazardous Substances Data)

Usage

General Description

4-HYDRAZINO-3-NITROPYRIDINE is a chemical compound with the molecular formula C5H5N5O2. It is a nitropyridine derivative with a hydrazino group attached to the third carbon atom. 4-HYDRAZINO-3-NITROPYRIDINE is mainly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. It is a yellow crystalline solid that is sparingly soluble in water and commonly used in research and development laboratories for its potential applications in the fields of medicine and agriculture. The chemical is also known to be potentially hazardous and should be handled with caution.

InChI:InChI=1/C5H6N4O2/c6-8-4-1-2-7-3-5(4)9(10)11/h1-3H,6H2,(H,7,8)

Upstream product

• 5435-54-1 4-hydroxy-3-nitropyridine 
• 31872-62-5 4-methoxy-3-nitro-pyridine 

Downstream Products

• 1092790-41-4 1-(3-nitropyridin-4-yl)-5-aminopyrazole-4-carbonitrile 
• 121845-43-0 2-(3-amino-4-pyridinyl)-4-(trifluoromethyl)benzoic acid hydrazide hydrochloride 
• 121845-44-1 3-<4-(trifluoromethyl)phenyl>-1,2-dihydropyrido<3,4-e>-1,2,4-triazine hydrochloride 
• 121845-87-2 3-ethyl-1,2,3,4-tetrahydro-3-(phenylmethyl)pyrido<3,4-e>-1,2,4-triazine hydrochloride 
• 121845-59-8 3-[4-(trifluoromethyl)phenyl]pyrido[3,4-e]-1,2,4-triazine 

Relevant articles and documents

Comparison of the effects of 5- and 6-HOAt on model peptide coupling reactions relative to the cases for the 4- and 7-isomers

(equation presented) Synthesis of 5- and 6-HOAt has completed the full set of the four HOAt isomers derived from HOBt by insertion of a single nitrogen atom in the benzenoid nucleus. Comparison of the reactivity of all four isomers in model peptide coupling reactions has confirmed the unique character of the 7-isomer in promoting selectivity and maintaining configuration at the reactive carboxylic acid residue.

Some new methods for preparing 2,3- and 3,4-diaminopyridines

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