335596-00-4Relevant academic research and scientific papers
A short and practical route to 3-O-benzoyl azidosphingosine
Ohlsson, Joergen,Magnusson, Goeran
, p. 91 - 94 (2001)
A short and practical route to 3-O-benzoyl azidosphingosine from D-xylose is described. The synthesis avoids the use of expensive and hazardous chemicals (i.e. mercury salts), and it is reproducible up to at least a 20 g scale. Furthermore, the synthesis proceeds to 3-O-benzoyl azidosphingosine with a minimum of protection group manipulation, by exploiting a regioselective protection of the primary HO-1 with thexyldimethylsilyl chloride.
