3356-29-4

Upstream product

• 589-57-1 diethyl phosphorylchloridite 
• 78-27-3 1-Ethynylcyclohexan-1-ol 
• 6209-75-2 1-ethynyl-1-chlorocyclohexane 
• 762-04-9 phosphonic acid diethyl ester 
• 5240-32-4 1-acetoxy-1-ethynyl cyclohexane 

Downstream Products

• 88126-92-5 2-Chloro-4-(4-chloro-phenylselanyl)-1-oxa-2-phospha-spiro[4.5]dec-3-ene 2-oxide 
• 88126-90-3 4-(4-Chloro-phenylselanyl)-2-isopropoxy-1-oxa-2-phospha-spiro[4.5]dec-3-ene 2-oxide 
• 88126-89-0 4-(4-Chloro-phenylselanyl)-2-propoxy-1-oxa-2-phospha-spiro[4.5]dec-3-ene 2-oxide 
• 107966-50-7 2-Ethoxy-4-phenylsulfanyl-1-oxa-2-phospha-spiro[4.5]dec-3-ene 2-oxide 
• 85318-32-7 2-ethoxy-5,5-pentamethylene-4-(phenylseleno)-1,2-oxaphosphol-3-ene 2-oxide 
• 145984-22-1 C₂₁H₄₈N₂O₃P₂Si₃ 

Relevant academic research and scientific papers

Convenient synthesis of allenylphosphoryl compounds: Via Cu-catalysed couplings of P(O)H compounds with propargyl acetates

A novel Cu-catalysed substitution reaction of propargyl acetates with P(O)H compounds is developed to afford allenylphosphoryl compounds via C-P bond coupling in high yields under mild conditions. A plausible mechanism involving the nucleophilic interception of the Cu-allenylidene intermediates is proposed.

Novel, stereoselective and stereospecific synthesis of allenylphosphonates and related compounds via palladium-catalyzed propargylic substitution

We have developed a novel method for the synthesis of allenylphosphonates and related compounds based on a palladium(0)-catalyzed reaction of propargylic derivatives with H-phosphonate, H-phosphonothioate, H-phosphonoselenoate, and H-phosphinate esters. The reaction is stereoselective and stereospecific, and provides a convenient entry to a vast array of allenylphosphonates and their analogues with diverse substitution patterns in the allenic moiety and at the phosphorus center. Some mechanistic aspects of this new reaction were also investigated. Copyright

Palladium-catalyzed propargylic substitution with phosphorus nucleophiles: Efficient, stereoselective synthesis of allenylphosphonates and related compounds

A new, efficient method is developed, based on a palladium(0)-catalyzed reaction of propargylic derivatives with various phosphorus nucleophiles, to produce allenylphosphonates and their analogues with defined stereochemistry in the allenic and the phosph

PHOSPHOR- UND SCHWEFELSUBSTITUIERTE ALLENE IN DER SYNTHESE I : EINFACHE SYNTHESE VON β-KETOPHOSPHONATEN AUS 1-ALKIN-3-OLEN

Allenic phosphonates, readily accessible from 1-alkin-3-ols, the addition products of 1-alkines to aldehydes or ketones, can be transformed to β-ketophosphonates by nucleophilic addition of diethylamine and subsequent hydrolysis of the formed enamines.