3356-92-1

Usage

Uses

Used in Organic Synthesis:
5-bromo-3-phenyl-oxazole is used as a building block for the synthesis of various pharmaceutical compounds and biologically active molecules due to its unique structural properties and reactivity.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-bromo-3-phenyl-oxazole serves as a precursor for the development of new drugs, contributing to drug discovery efforts.
Used in Drug Discovery:
5-bromo-3-phenyl-oxazole is utilized as a key component in the design and synthesis of potential drug candidates, owing to its diverse chemical reactivity and structural properties.
Used in Agrochemicals:
5-bromo-3-phenyl-oxazole finds applications in the agrochemical industry, where it may be employed in the development of new pesticides or other agrochemical products, leveraging its unique chemical properties.
Used in Material Science:
5-bromo-3-phenyl-oxazole also has potential uses in material science, where its structural and chemical characteristics can be harnessed to create new materials with specific properties for various applications.

InChI:InChI=1/C9H6BrNO/c10-9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H

Upstream product

• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 3234-51-3 1,1-dibromo-2-phenylcyclopropane 

Downstream Products

• 25388-16-3 toluene-4-sulfonic acid N'-(3-phenyl-isoxazol-3-yl)-hydrazide 
• 94447-61-7 5-(benzyloxy)-3-phenylisoxazole 
• 10285-00-4 4-(3-phenylisoxazol-5-yl)morpholine 
• 1006-65-1 3-phenylisoxazole 
• 25388-10-7 benzaldehyde (3-phenyl-isoxazol-5-yl)-hydrazone 
• 129681-60-3 ethyl (4-bromo-3-phenylisoxazol-5-yl)cyanoacetate 
• 129681-58-9 ethyl isopropyl(3-phenylisoxazol-5-yl)cyanoacetate 
• 129681-57-8 methyl n-propyl(3-phenylisoxazol-5-yl)cyanoacetate 
• 129681-56-7 methyl ethyl(3-phenylisoxazol-5-yl)cyanoacetate 
• 129681-59-0 2-(3-phenylisoxazol-5-yl)acetonitrile 
• 42457-29-4 3-phenyl-5-trans-styrylisoxazole 
• 6463-64-5 3,3'-diphenyl-5,5'-biisoxazole 
• 81190-87-6 ethyl trans-3-phenyl-5-isoxazoleacrylate 
• 129681-49-8 sodio(3-phenylisoxazol-5-yl)malononitrile 

Relevant academic research and scientific papers

General Platform for the Conversion of Isoxazol-5-ones to 3,5-Disubstituted Isoxazoles via Nucleophilic Substitutions and Palladium Catalyzed Cross-Coupling Strategies

A general platform for the conversion of isoxazol-5-ones to 3,5-disubstituted isoxazoles has been developed via a two-step strategy. The first step leads to the formation of 5-(pseudo)halogenated isoxazoles, while in the second, a variety of heteroalkyl-, heteroaryl-, alkyl-, alkenyl-, alkynyl- and aryl-chains can be installed via nucleophilic substitutions or palladium catalyzed cross-coupling reactions.

Transformations of gem-dibromoarylcyclopropanes under nitrosation conditions on treatment with NOCl·(SO3)n

The reaction of 2-aryl-1,1-dibromocyclopropanes with adduct NOCl·(SO3)n leading to 3-aryl-5-bromoisoxazoles as a result of nitrosation—heterocyclization of the cyclopropane ring was studied. The reaction is accompanied with electroph

Nitrosation of 2-aryl-1,1-dibromocyclopropanes: Synthesis of 3-aryl-5-bromoisoxazoles

An efficient transformation of 2-aryl-1,1-dibromocyclopropanes under the action of sulfur trioxide activated nitrosyl chloride has been developed, providing a series of arylated 5-bromoisoxazoles with good yields. It is noteworthy that under the reported