129681-59-0Relevant academic research and scientific papers
Product selectivity of thermal Buchner reaction of methyl 2-(3-arylisoxazol-5-yl)-2-diazoacetates with benzene, naphthalene and mesitylene, and ring-opening/closing reaction of products
Serebryannikova, Anna V.,Galenko, Ekaterina E.,Novikov, Mikhail S.,Khlebnikov, Alexander F.
, (2021/05/04)
Methyl 2-(3-arylisoxazol-5-yl)-2-diazoacetates were synthesized and the product selectivity of their thermal Buchner reaction with benzene, naphthalene and mesitylene was studied. The reaction of the isoxazolyl-substituted diazoacetates with benzene gave
Ramoplanin derivatives possessing antibacterial activity
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Page/Page column 39; 56, (2010/11/23)
Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
Chemical transformations on 6-aryl-3-cyano4-methylthio-pyran-2(h)-ones: Synthetic and structural studies on novel N-phenylpyrazoles and N-phenylpyrazolylcoumarins
Kumar, Ajay,Malhotra, Sanjay,Vats, Archana,Himanshu,Singh, Sanjay K.,Sharma, Sunil K.,Prasad, Ashok K.,Errington, William,Olsen, Carl E.,Jain, Subhash C.,Parmar, Virinder S.
, p. 360 - 367 (2007/10/03)
Seven 6-aryl-3-cyano-4-methylthiopyran-2(H)ones 1-7 have been prepared and used for the efficient synthesis of twelve 1,3-diaryl-5-cyanomethylpyrazoles 8-19, one 3-cyanomethyl-5-(3,4-methylenedioxyphenyl)pyrazole 22 and one 5-cyanomethyl-3-phenylisoxazole
Synthetic and mass spectral fragmentation studies on trisubstituted 2H-pyran-2-ones and comparative EIMS behaviour of biologically active 3,5-disubstituted pyrazoles and isoxazoles
Parmar, Virinder S.,Jain, Subhash C.,Jha, Amitabh,Kumar, Naresh,Kumar, Ajay,Vats, Archana,Jha, Hriday N.,Mukherjee, Shubhasish,Singh, Sanjay K.,Jennings, Keith R.,Summerfield, Scott G.,Errington, William,Olsen, Carl E.
, p. 872 - 879 (2007/10/03)
Eight 3-cyano-4-thiomethyl-6-aryl-2H-pyran-2-ones 1-8 and three 3-cyano-4-(N,N-dimethy)amino-6-aryl-2H-pyran-2-ones 9-11 have been synthesised and their detailed mass fragmentation pattern alongwith the X-ray crystal structure of a novel pyrone 5 have been studied. In addition, a comparative EIMS behaviour of 3,5-disubstituted pyrazoles 16-23 and isoxazoles 12-15 is reported. The pyrazole derivative 23 has been found to possess strong anti-invasive activity against human breast carcinoma cells.
FORMATION AND REACTIVITY OF HIGHLY STABILIZED CARBANIONS AND ENOLATES BY Pd-CATALYZED ALKYLATION OF HETEROCYCLIC COMPOUNDS
Sakakibara, Tsutomu,Kume, Takashi,Shimohara, Kumiko,Fujishima, Hiroshi,Hara, Shunpei,Shimoda, Toshifumi
, p. 459 - 472 (2007/10/02)
Highly stabilized carbanion and enolate salts, heterocycle-substituted sodiomalononitrile and sodiocyanoacetates, were synthesized via Pd-catalyzed ring-alkylation of bromoheterocyclic compounds and shown to be useful intermediates for the synthesis of va
