33578-23-3

Basic information

• Product Name: 1-(diphenylphosphinoyl)pentan-2-one
• Synonyms: 1-(diphenylphosphinoyl)pentan-2-one
• CAS NO: 33578-23-3
• Molecular Weight: 286.31
• Mol File: 33578-23-3.mol

Chemical Properties

• CAS DataBase Reference: 1-(diphenylphosphinoyl)pentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(diphenylphosphinoyl)pentan-2-one(33578-23-3)
• EPA Substance Registry System: 1-(diphenylphosphinoyl)pentan-2-one(33578-23-3)

Safety Data

• Hazardous Substances Data: 33578-23-3(Hazardous Substances Data)

Upstream product

• 23040-22-4 (diphenylphosphoryl)acetonitrile 
• 627-19-0 1-Pentyne 
• 4559-70-0 Diphenylphosphine oxide 
• 719-80-2 Ethyl diphenylphosphinite 
• 74-96-4 ethyl bromide 
• 1733-52-4 1-(diphenylphosphinoyl)propan-2-one 

Relevant articles and documents

Silver-Catalyzed Oxyphosphorylation of Unactivated Alkynes

Here, we describe an application of hydroazidation in the instant activation of alkynes for achieving the oxyphosphorylation of unactivated alkynes with diarylphosphinoyl radicals under mild reaction conditions. This reaction provides a method for accessing β-ketophosphine oxides and phosphorus-containing pyrroles. (Figure presented.).

Copper catalyzed one-pot synthesis of β-ketophosphine oxides from ketones and H-phosphine oxides

A facile and efficient copper catalyzed one-pot method has been developed for the formation of β-ketophosphine oxides from ketones and H-phosphine oxides under air at room temperature, in which vinylhydrazinedicarboxylate was formed as the key intermediate. Preliminary mechanistic studies indicated that the reaction might involve a radical process and carbonyl oxygen atom of β-ketophosphine oxides came from molecular oxygen.

Reactions of Anions from α-Diphenylphosphinoyl Ketones with Electrophiles

Anions from α-Ph2P(O)-ketones do not give Horner-Wittig reactions but do react with alkyl halides, including α-halogenocarbonyl compounds, and Michael acceptors.The products may be stereoselectively reduced.