3358-50-7Relevant academic research and scientific papers
The unexpected synthesis of 2-thioxo-1-imidazolidinecarboxamides from 2-oxo-1-imidazolidinethiocarbonyl chloride
Pilling, Garry M.,Johnson, Robert E.
, p. 6763 - 6764 (2007/10/02)
The reaction of 2-oxo-1-imidazolidinethiocarbonyl chloride with aromatic amines gives N-aryl-2-thioxo-1-imidazolidinecarboxamides. This finding is consistent with an ethylene isocyanate isothiocyanate intermediate.
NOVEL HETEROPENTALENES. SYNTHESIS OF HETEROPENTALENES FROM TETRAHYDROIMIDAZO -(1,2,4)-THIADIAZOLES AND CONVERSION OF CERTAIN HETEROPENTALENES TO BENZOTHIAZOLE DERIVATIVES
Beer, Roger J. S.,Singh, Hardev,Wright, David,Hansen, Lars Kr.
, p. 2485 - 2488 (2007/10/02)
Oxidation of 1-phenylcarbamoylimidazolidine-2-thione gives 2,3,5,6-tetrahydro-2-phenylimidazo-(1,2,4)-thiadiazole-3-one which undergoes addition reactions with heterocumulenes leading to various heteropentalenes.Oxidation of 1-phenylthiocarbamoylimidazolidine-2-thione yields 1-(benzothiazol-2-yl)-imidazolidine-2-thione, also obtained by acid catalysed decomposition of 3,4-ethano-2,3,4,5-tetrahydro-2,5-bisphenylimino-1,6,6aSIV-trithia-3,4-diazapentalene.A similar acid catalysed decomposition to a benzothiazole occurs with 2,3,4,5-tetrahydro-1,6-diphenyl-3,4-propano-6aSIV-thia-1,3,4,6-tetraazapentalene-2,5-dithione.
Syntheses of imidazoline-2-thiol-derivatives with potential tuberculostatic activity. I. Reactions of imidazoline-2-thiol with some isocyanates and isothiocyanates
Sawlewicz,Wisterowicz,Janowiec
, p. 403 - 411 (2007/10/08)
Imidazoline-2-thiol was reacted with aromatic isocyanates or isothiocyanates to yield respective N-arylcarbamyl and N-arylthiocarbamyl derivatives. The obtained compounds were subjected to cyanoethylation and aminomethylation reactions. The performed syntheses afforded 34 new derivatives of imidazoline-2-thiol, structures of which have been confirmed by elementary and spectral analysis. Tuberculostatic activity of the compounds was examined.
