33604-58-9Relevant academic research and scientific papers
Facile formations of ketals of α, α-dihaloacetophenones
Bovonsombat, Pakorn,McNelis, Edward
, p. 4123 - 4126 (1992)
Ketals of α,α-dihaloacetophenones are prepared in high yields from phenylethyne and N-halosuccinimide with catalytic quantities of p-toluenesulfonic acid.
Iron(III) catalyzed halo-functionalization of alkynes
Catano, Bryant,Lee, John,Kim, Claudia,Farrell, David,Petersen, Jeffrey L.,Xing, Yalan
supporting information, p. 4124 - 4127 (2015/08/03)
Abstract Aromatic and aliphatic alkynes can be halo-functionalized to α,α-dihalodimethyl ketals catalyzed by FeCl3 in excellent yields. MeOH is used as a nucleophilic solvent and N-halosuccinimide as the halogen source for this efficient transformation. The resulting α,α-dibromodimethyl ketals can be converted to the corresponding α,α-dibromoketones by treatment with 8% FeCl3 in silica gel.
Facile generation of α,α-dibromodimethyl ketals from alkynes using TsNBr2
Rajbongshi, Kamal Krishna,Phukan, Prodeep
, p. 1877 - 1878 (2014/03/21)
TsNBr2 reacts with alkyne in the presence of methanol to form α,α-dibromodimethyl ketals instantaneously. The reaction proceeds smoothly at room temperature without using any other catalyst. The one step reaction can be carried out with both ar
Solvent incorporation in bromination of alkynes with tetrabutylammonium tribromide in methanol
Berthelot, Jacques,Benammar, Yamina,Desmazieres, Bernard
, p. 2865 - 2876 (2007/10/03)
The reaction of tetrabutylammonium tribromide (TBABr3) with mono and disubstituted alkynes in methanol at 20°C leads to the formation of mainly the corresponding α,α-dibromo, β,β-dimethoxyalkane and the E-(α,β)- dibromoalkene. The additions are faster using sonication.
