336156-84-4

Basic information

• Product Name: [2-hydroxy-1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [2-hydroxy-1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 336156-84-4
• Molecular Weight: 552.695
• Mol File: 336156-84-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-hydroxy-1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-hydroxy-1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester(336156-84-4)
• EPA Substance Registry System: [2-hydroxy-1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester(336156-84-4)

Safety Data

• Hazardous Substances Data: 336156-84-4(Hazardous Substances Data)

Upstream product

• 16681-77-9 1-methyl-1,2,3,4-tetrazole 

Downstream Products

• 908142-06-3 [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 908142-56-3 4-oxo-2-phenylmethanesulfonyl-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-amide 

Relevant articles and documents

Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: Transition state inhibitors

Bicyclic piperazinone based thrombin inhibitors of general structure 2 were prepared and evaluated in vitro and in vivo. These inhibitors, having in common an electrophilic basic trans-cyclohexylamine P1 residue, displayed high thrombin affinity, high selectivity against trypsin and good in vivo efficacy in the rat arterial thrombosis model.