908142-06-3

Basic information

• Product Name: [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 908142-06-3
• Molecular Weight: 550.679
• Mol File: 908142-06-3.mol

Chemical Properties

• CAS DataBase Reference: [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(908142-06-3)
• EPA Substance Registry System: [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(908142-06-3)

Safety Data

• Hazardous Substances Data: 908142-06-3(Hazardous Substances Data)

Upstream product

• 336156-84-4 [2-hydroxy-1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester 

Downstream Products

• 908142-56-3 4-oxo-2-phenylmethanesulfonyl-octahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [1-[4-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-cyclohexyl]-2-(1-methyl-1H-tetrazol-5-yl)-2-oxo-ethyl]-amide 

Relevant articles and documents

Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: Transition state inhibitors

Bicyclic piperazinone based thrombin inhibitors of general structure 2 were prepared and evaluated in vitro and in vivo. These inhibitors, having in common an electrophilic basic trans-cyclohexylamine P1 residue, displayed high thrombin affinity, high selectivity against trypsin and good in vivo efficacy in the rat arterial thrombosis model.