33617-59-3

Basic information

• Product Name: 4-(hydroxymethyl)resorcinol
• Synonyms: 4-(hydroxymethyl)resorcinol;4-(hydroxymethyl)benzene-1,3-diol;1,3-Benzenediol,4-(hydroxymethyl)-;4-(hydroxymethyl)-1,3-Benzenediol;4-Methylolresorcinol
• CAS NO: 33617-59-3
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.13662
• EINECS: 251-597-1
• Mol File: 33617-59-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 363.4°Cat760mmHg
• Flash Point: 190.6°C
• Appearance: /
• Density: 1.399g/cm³
• Vapor Pressure: 6.43E-06mmHg at 25°C
• Refractive Index: 1.648
• PKA: 9.53±0.18(Predicted)
• CAS DataBase Reference: 4-(hydroxymethyl)resorcinol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(hydroxymethyl)resorcinol(33617-59-3)
• EPA Substance Registry System: 4-(hydroxymethyl)resorcinol(33617-59-3)

Safety Data

• Hazardous Substances Data: 33617-59-3(Hazardous Substances Data)

Usage

General Description

4-(hydroxymethyl)resorcinol, also known as p-hydroxymethyl resorcinol, is a chemical compound that is commonly used in cosmetic and personal care products. It is a derivative of resorcinol, a chemical with antiseptic and disinfectant properties, and it is used in skincare products for its brightening and anti-aging effects. 4-(hydroxymethyl)resorcinol is known to inhibit tyrosinase, which is an enzyme involved in the production of melanin, making it effective in reducing the appearance of age spots and hyperpigmentation. Additionally, it has antioxidant properties, helping to protect the skin from environmental damage and oxidative stress. Overall, 4-(hydroxymethyl)resorcinol is a versatile and beneficial ingredient in skincare formulations, providing a range of protective and brightening effects for the skin.

InChI:InChI=1/C7H8O3/c8-4-5-1-2-6(9)3-7(5)10/h1-3,8-10H,4H2

Upstream product

• 50-00-0 formaldehyd 
• 108-46-3 recorcinol 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 89-86-1 4-hydroxysalicylic acid 
• 13246-46-3 2,4-dibenzyloxybenzaldehyde 
• 33617-58-2 2,4-dibenzyloxybenzyl alcohol 

Downstream Products

• 131088-02-3 2,4-dihydroxy-5-chlorobenzaldehyde 
• 3147-45-3 2,4-dihydroxybenzamide 
• 89-86-1 4-hydroxysalicylic acid 

Relevant articles and documents

Mild-temperature hydrogenation of carbonyls over Co-ZIF-9 derived Co-ZIF-x nanoparticle catalyst

Benzimidazole and metal cobalt salts were employed in the synthesis of Co-ZIF-9 by solvothermal crystallization. Highly active catalysts for selective hydrogenation of carbonyl compounds were developed. The optimal nanocatalyst Co-ZIF-350 manifested remarkable activity and selectivity for the hydrogenation of cyclohexanone under mild conditions. Catalytic conversion of cyclohexanone reached the highest over the catalyst of Co-ZIF-9-pyrolyzed at 350 °C for 2 h, in which the conversion of cyclohexanone was 100 % and the selectivity of cyclohexanol was ＞99 % at 50 °C. A wide scope of ketones/aromatic aldehydes could be selectively reduced to the corresponding alcohols with high yields. Importantly, the nanocatalyst Co-ZIF-350 presented good tolerance of substrates with various functional groups under mild conditions.

Phenyl benzofuran compound as well as preparation method, composition, and medical applications thereof

The invention discloses a phenyl benzofuran compound as well as a preparation method, a composition, and medical applications thereof. The structure of the phenyl benzofuran compound is: characterizedin that the formulas are shown in the specificationdescription. The invention discloses a traditional Chinese medicine extracting method of the phenyl benzofuran compound using a moonseed rhizomerhizoma menispermirough powder as a raw material.The invention discloses a chemical synthetic method of phenyl benzofuran compound using 2,4-dihydroxybenzoic acid as starting materials.The invention discloses a composition containing the phenyl benzofuran compound, and an active ingredient of the composition is the phenyl benzofuran compound.The invention also discloses the application of the phenyl benzofuran compound in the preparation of a drug or food or health product preventing or treating a tumor, and the tumor is nasopharyngeal carcinoma.According to the invention, the phenyl benzofuran compound can be prepared by the traditional Chinese medicine extracting method and the chemical synthetic method, and meanwhile, an in vitro tumor cell experiment proves that phenyl benzofuran has an inhibiting effect on both nasopharyngeal carcinoma cells CNE-1 and CNE-2.