33621-62-4

Basic information

• Product Name: 5-(4-BROMOPHENYL)-1,3,4-OXADIAZOL-2-AMINE
• Synonyms: 5-(4-BROMOPHENYL)-1,3,4-OXADIAZOL-2-AMINE;IFLAB-BB F2146-0039;UKRORGSYN-BB BBV-048898;5-(4-BroMo-phenyl)-[1,3,4]oxadiazol-2-ylaMine
• CAS NO: 33621-62-4
• Molecular Formula: C₈H₆BrN₃O
• Molecular Weight: 240.07
• Mol File: 33621-62-4.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-(4-BROMOPHENYL)-1,3,4-OXADIAZOL-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-BROMOPHENYL)-1,3,4-OXADIAZOL-2-AMINE(33621-62-4)
• EPA Substance Registry System: 5-(4-BROMOPHENYL)-1,3,4-OXADIAZOL-2-AMINE(33621-62-4)

Safety Data

• Hazardous Substances Data: 33621-62-4(Hazardous Substances Data)

Usage

General Description

5-(4-Bromophenyl)-1,3,4-oxadiazol-2-amine is a chemical compound that belongs to the oxadiazole family, which is known for its diverse range of biological and pharmacological activities. This specific compound contains a 1,3,4-oxadiazole ring with an amine group and a bromophenyl substituent. Oxadiazole derivatives have been widely studied for their potential as antibacterial, antifungal, anticancer, and anti-inflammatory agents. The presence of a bromine atom in the phenyl group of this compound can also enhance its reactivity and biological activity, making it a valuable candidate for further research and development in the pharmaceutical industry.

Upstream product

• 120445-43-4 2-(4-bromobenzylidene)hydrazinecarboxamide 
• 1122-91-4 4-bromo-benzaldehyde 
• 563-41-7 semicarbazide hydrochloride 
• 586-76-5 4-Bromobenzoic acid 
• 4426-72-6 hydrazine carboxamide 
• 506-68-3 bromocyane 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 5933-32-4 4-bromobenzoic acid hydrazide 
• 199339-12-3 2-[(Z)-5-(4-Bromo-phenyl)-[1,3,4]oxadiazol-2-ylimino]-5-phenyl-thiazolidin-4-one 
• 199339-18-9 2-[(Z)-5-(4-Bromo-phenyl)-[1,3,4]oxadiazol-2-ylimino]-5-methyl-thiazolidin-4-one 

Downstream Products

• 131548-11-3 (E)-N-[5-(4-Bromo-phenyl)-[1,3,4]oxadiazol-2-yl]-3-phenyl-acrylamide 
• 62287-34-7 3-(4-Bromophenyl)-5-ethoxy-1,2,4-triazole 
• 131548-08-8 N-[5-(4-Bromo-phenyl)-[1,3,4]oxadiazol-2-yl]-2-methyl-acrylamide 
• 131548-04-4 N-[5-(4-Bromo-phenyl)-[1,3,4]oxadiazol-2-yl]-acrylamide 
• 135790-31-7 2-[5-(4-Bromo-phenyl)-[1,3,4]oxadiazol-2-ylamino]-N-(2-methyl-4-oxo-4H-quinazolin-3-yl)-acetamide 
• 127461-28-3 C₈H₄BrN₃O₂S 
• 1258277-19-8 2-(2-phenyl-1,3,4-oxodiazol-5-yl)benzisoselenazol-3(2H)-one 

Relevant articles and documents

In Silico Study and In Vitro Evaluation of Novel Synthesized Quinolone Derivatives Having Five-Membered Heterocyclic Moieties

Infectious diseases are caused by pathogens, such as viruses, bacteria, fungi, and parasites. Quinolones work by inhibition of bacterial topoisomerase IV and/or gyrase, a group of oxadiazole derivatives were incorporated into C7 piperazine ring of Gatiflo

Synthesis of indole-tethered [1,3,4]thiadiazolo and [1,3,4]oxadiazolo[3,2-a]pyrimidin-5-one hybrids as anti-pancreatic cancer agents

New indole-tethered [1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (8a-j) and [1,3,4]oxadiazolo[3,2-a]pyrimidin-5-one hybrids (9a-e) were synthesized using [4+2] cycloaddition reactions of functionalized 1,3-diazabuta-1,3-dienes with indole-ketenes. All molecul

Ultrasound-assisted synthesis of 2-amino-1,3,4-oxadiazoles through NBS-mediated oxidative cyclization of semicarbazones

A ultrasound-assisted oxidative cyclization of semicarbazones using N-bromosuccinimide in the presence of sodium acetate was established providing efficient and rapid access to a variety of 2-amino-1,3,4-oxadiazoles. Moreover, the new synthetic protocol provides a simple procedure utilizing a safer oxidizing system that affords the target products in high regioselectivity, satisfactory yields, and elevated purities.