33626-64-1Relevant academic research and scientific papers
Δ2-1,2,4-oxadiazolines by condensation of amidoximes with ketones and aldehydes
Lessel
, p. 383 - 389 (2007/10/02)
Using acetic acid as a solvent, ketones and aromatic aldehydes react with amidoximes 1 to cyclic products, Δ2-1,2,4-oxadiazolines 3. The lack of reactivity in neutral milieu is explained by MNDO calculations. Protonated carbonyl compounds are discussed to be the reactive species.
