336817-83-5

Basic information

• Product Name: Tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-ethyl ester
• Synonyms: Tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-ethyl ester
• CAS NO: 336817-83-5
• Molecular Formula: C₁₇H₃₀N₂O₆
• Molecular Weight: 0
• Mol File: 336817-83-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-ethyl ester(336817-83-5)
• EPA Substance Registry System: Tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-ethyl ester(336817-83-5)

Safety Data

• Hazardous Substances Data: 336817-83-5(Hazardous Substances Data)

Upstream product

• 1397581-12-2 2-(N,N'-di-tert-butoxycarbonylhydrazino)hex-5-enoic acid ethyl ester 
• 31696-00-1 diethyl 2-(3-butenyl)malonate 
• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 1397582-53-4 C₁₈H₃₄N₂O₉S 
• 1397582-07-8 2-(N,N'-di-tert-butoxycarbonylhydrazino)-5-hydroxypentanoic acid ethyl ester 
• 1397581-01-9 2-(N,N'-di-tert-butoxycarbonylhydrazino)pent-4-enoic acid ethyl ester 

Downstream Products

• 336817-85-7 1,2-di(tert-butoxycarbonyl)-3-(4-bromobenzyl)hexahydropyridazine-3-carboxylic acid ethyl ester 
• 1219380-72-9 N,N'-di-tert-butoxycarbonylpiperazic acid 

Relevant articles and documents

Novel linker compound and Site-Specific compounds of Antibody-Drug Conjugate Comprising the Same

The present invention relates to a novel linker compound, and relates to a site-specific antibody-drug conjugate (ADC) compound comprising the same, a method for manufacturing the same, and an anticancer composition comprising the same as an active component. The linker compound produces a uniform ADC compound with excellent site specificity in manufacturing an ADC compound, and the ADC compound comprising the same exhibits an excellent anticancer effect.COPYRIGHT KIPO 2020

Synthesis of cyclic α-hydrazino acids

Synthesis of five-, six-, seven-, eight-, and nine-membered cyclic α-hydrazino acids from a common starting material 'diethylmalonate' with 26, 16, 34, 13.5, and 13.33% overall yields is described. Sequential allylation or homoallylation and electrophilic amination followed by cyclization gave the desired rings. The methyl esters of eight- and nine-membered rings were synthesized by RCM and the corresponding free acids were generated after hydrolysis in the presence of 1 M BBr3 solution in DCM.

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The present invention relates to a compound of formula: (I), or a pharmaceutically acceptable salt thereof.