336883-67-1

Basic information

• Product Name: toluene-4-sulfonic acid 2-(2,2-diethyl[1,3]dioxolan-4-yl)ethyl ester
• CAS NO: 336883-67-1
• Molecular Weight: 328.43
• Mol File: 336883-67-1.mol

Chemical Properties

• CAS DataBase Reference: toluene-4-sulfonic acid 2-(2,2-diethyl[1,3]dioxolan-4-yl)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: toluene-4-sulfonic acid 2-(2,2-diethyl[1,3]dioxolan-4-yl)ethyl ester(336883-67-1)
• EPA Substance Registry System: toluene-4-sulfonic acid 2-(2,2-diethyl[1,3]dioxolan-4-yl)ethyl ester(336883-67-1)

Safety Data

• Hazardous Substances Data: 336883-67-1(Hazardous Substances Data)

Upstream product

• 25636-49-1 3,3-dimethoxypentane 
• 98-59-9 p-toluenesulfonyl chloride 
• 149716-35-8 2-(2,2-diethyl[1,3]dioxolan-4-yl)ethanol 

Relevant articles and documents

Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir

We synthesized bicyclic ether sialidase inhibitors such as tetrahydro-furan-2-yl, tetrahydro-pyran-2-yl, and oxepan-2-yl derivatives related to zanamivir. These compounds substituted by diol at the C-3′ and C-4′ positions resulted in the retention of low nanomolar inhibitory activities against not only influenza A virus sialidase but also influenza A virus in cell culture. Compound 11a in particular showed comparable efficacy in vivo relative to that of oseltamivir phosphate.