337-28-0

Basic information

• Product Name: PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL
• Synonyms: PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL;1-ethoxy-2,2,3,3,3-pentafluoro-1-propanol;1-ethoxy-2,2,3,3,3-pentafluoropropan-1-ol
• CAS NO: 337-28-0
• Molecular Formula: C₅H₇F₅O₂
• Molecular Weight: 194.1
• EINECS: 206-413-4
• Mol File: 337-28-0.mol

Chemical Properties

• Boiling Point: 108.8°Cat760mmHg
• Flash Point: 58.1°C
• Appearance: /
• Density: 1.3331 (estimate)
• Vapor Pressure: 13.5mmHg at 25°C
• Refractive Index: 1.331
• CAS DataBase Reference: PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL(337-28-0)
• EPA Substance Registry System: PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL(337-28-0)

Safety Data

• Hazardous Substances Data: 337-28-0(Hazardous Substances Data)

Usage

Uses

Used in Flavoring Industry:
PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL is used as a flavoring agent for its fruity odor, enhancing the taste and aroma profiles of food and beverages.
Used in Organic Synthesis:
PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL is used as a reagent in organic synthesis, contributing to the creation of a variety of chemical compounds due to its stable and low reactive nature.
Used in Chemical Processes as a Solvent:
In the chemical industry, PENTAFLUOROPROPIONALDEHYDE ETHYL HEMIACETAL is utilized as a solvent in different processes, facilitating reactions and improving the efficiency of chemical operations.

InChI:InChI=1/C5H7F5O2/c1-2-12-3(11)4(6,7)5(8,9)10/h3,11H,2H2,1H3

Upstream product

• 422-06-0 2,2,3,3,3-Pentafluoro-propionaldehyde 
• 64-17-5 ethanol 
• 426-65-3 ethyl Pentafluoropropionate 

Downstream Products

• 1292820-54-2 C₁₁H₁₀F₅N 
• 1292820-93-9 C₁₀H₈F₅N 
• 189396-84-7 C₁₀H₈F₅NO 

Relevant articles and documents

HETEROARYL COMPOUNDS WITH A-CYCLIC BRIDGING UNIT

This invention relates to certain heteroaryl compounds which may be used as medicaments, more specifically as medicaments for treating animals. The medicament can be used for the treatment of parasitic infections such as helminth infections and the treatment of parasitosis caused by such infections. This invention also relates to uses of the compounds to make medicaments and treatments comprising the administration of the compounds to animals in need of the treatments. This invention also relates to pharmaceutical compositions and kits comprising the compounds.

N-HETEROARYL COMPOUNDS

This invention relates to certain N-heteroaryl compounds that are generally useful as medicaments, more specifically as medicaments for animals. The medicament can preferably be used for the treatment of helminth infections and the treatment of parasitosis, such as caused by helminth infections. This invention also relates to uses of the compounds to make medicaments and treatments comprising the administration of the compounds to animals in need of the treatments. This invention also relates to novel N-heteroaryl compounds and the preparation of said compounds. Moreover this invention relates to pharmaceutical compositions and kits comprising the compounds.

N-HETEROARYL COMPOUNDS WITH CYCLIC BRIDGING UNIT FOR THE TREATMENT OF PARASITIC DISEASES

This invention relates to certain N-heteroaryl compounds that are generally useful as medicaments, more specifically as medicaments for animals. The medicament can preferably be used for the treatment of helminth infections and the treatment of parasitosis, such as caused by helminth infections. This invention also relates to uses of the compounds to make medicaments and treatments comprising the administration of the compounds to animals in need of the treatments. This invention also relates to the preparation of the N-heteroaryl compounds. Moreover this invention relates to pharmaceutical compositions and kits comprising the compounds.

Highly diastereo- and enantioselective vinylogous Mannich reactions of fluorinated aldimines with siloxyfurans

A highly regio- and enantioselective asymmetric vinylogous Mannich reaction of readily available fluorinated aldimines bearing a chiral auxiliary [(S)-1-phenylethyl group] with siloxyfurans to afford chiral fluorine-containing γ-butenolide or γ-lactone derivatives has been developed in the presence of silver acetate (10 mol%) and axially chiral phosphine-oxazoline ligand L1 (11 mol%). In most cases, the corresponding fluorinated adducts were obtained in high yields, good to excellent enantiomeric excesses and up to > 20:1 dr.