33716-47-1Relevant academic research and scientific papers
C- and O-alkylation with α-Haloketones of the adamantane series
Danilin,Purygin,Makarova,Zemtsova,Moiseev
, p. 56 - 61 (2001)
Reactions of 1-adamantyl bromomethyl ketone and 1-(1-adamantyl)-3-bromo-2-propanone with acetylacetone and ethyl acetoacetate in a mixture of dry diethyl ether with anhydrous methanol in the presence of sodium methoxide afforded 3-(1-adamantylcarbonylmethyl)-2,4-pentanedione, ethyl 2-(1-adamantylcarbonylmethyl)-3-oxobutanoate, 4-acetyl-1-(1-adamantyl)-2,5-hexanedione, and ethyl 2-acetyl-5-(-adamantyl)-4-oxopentanoate. The Knoevenagel-Cope reactions of 1-adamantyl bromomethyl ketone and 1-(1-adamantyl)-3-bromo-2-propanone with diethyl malonate yielded, respectively, diethyl 1-(1-adamantyl)-2-bromoethylidenemalonate and diethyl 1-(1-adamantylmethyl)-2-bromoethylidenemalonate. O-Alkylation of ethyl acetoacetate with 1-adamantyl bromomethyl ketone gave ethyl 3-(1-adamantylcarbonylmethoxy)-2-butenoate. Carboxylic acids reacted with 1-adamantyl bromomethyl ketone to form the corresponding 2-(1-adamantyl)-2-oxoethyl carboxylates.
INTRODUCTION D'UN SYSTEME "CAGE" DERIVE DE L'ADAMANTANE DANS LES ACIDES CARBOXYLIQUES, PAR ALKYLATION EN CATALYSE PAR TRANSFERT DE PHASE ET PAR UNE METHODE NON CATALYTIQUE
Hedayatullah, Mir
, p. 139 - 144 (2007/10/02)
The syntheses of new carboxylic esters of general type RCO2-CH2CO-Ad (Ad = 1-adamantyl), where R may be aliphatic or aromatic, have been achieved in high yield by reaction of the corresponding acides with an appropriate derivative of adamantane under phas
