33722-10-0Relevant academic research and scientific papers
Regioselective Synthesis of 1,4,5-Trisubstituted-1,2,3-Triazoles from Aryl Azides and Enaminones
De Nino, Antonio,Algieri, Vincenzo,Tallarida, Matteo A.,Constanzo, Paola,Pedrón, Manuel,Tejero, Tomás,Merino, Pedro,Maiuolo, Loredana
, p. 5725 - 5731 (2019/08/26)
A total regioselective synthesis of 1,4,5-trisubstituted-1,2,3-triazoles from aryl azides and enaminones is reported. The use of an ionic liquid in the presence of water and trimethylamine is crucial for the progress of the reaction. The process, consisti
A NHC-catalyzed 1,3-dipolar cycloaddition reaction of allyl ketones with azides: Direct access to 1,4,5-trisubstituted 1,2,3-triazoles
Yuan, Huijun,Zhang, Lili,Liu, Zhantao,Liu, Yang,Wang, Jian,Li, Wenjun
supporting information, p. 4286 - 4290 (2017/07/10)
A NHC-catalyzed 1,3-dipolar cycloaddition reaction of allyl ketones with azides has been developed. This strategy could generate 1,4,5-trisubstituted 1,2,3-triazoles in high yields and regioselectivities in the presence of a 20 mol% N-heterocyclic carbene catalyst. A broad substrate scope of this process is also presented.
Method for synthesizing 1,4,5-trisubstituted-1,2,3-triazole compound
-
Paragraph 0026; 0027; 0028, (2017/08/31)
The invention discloses a method for synthesizing a 1,4,5-trisubstituted-1,2,3-triazole compound under catalysis of carbine. The 1,4,5-trisubstituted-1,2,3-triazole compound is prepared by allowing allyl ketone and nitrine which are reacting raw materials to react in a reaction solvent in the presence of a catalyst which is carbine. The method has the advantages of mild reaction condition, easily available and low-price raw material, simple reacting operation and relatively high yield, provides a key frame structure for various natural product and medicine synthesis, and can be widely applied to industrial large-scale production.
Direct access to 1,2,3-triazoles through organocatalytic 1,3-dipolar cycloaddition reaction of allyl ketones with azides
Li, Wenjun,Du, Zhiyun,Huang, Jiayao,Jia, Qianfa,Zhang, Kun,Wang, Jian
, p. 3003 - 3006 (2014/06/10)
A general organocatalytic 1,3-dipolar cycloaddition reaction between allyl ketones and various azides is reported. The reaction is catalyzed by a secondary amine to generate substituted 1,2,3-triazoles with high levels of regioselectivity. This journal is the Partner Organisations 2014.
