337368-14-6

Basic information

• Product Name: 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine
• Synonyms: 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine;3-[(PhenylMethoxy)aMino]-N-[(phenylMethoxy)carbonyl]-L-alanin
• CAS NO: 337368-14-6
• Molecular Formula: C₁₈H₂₀N₂O₅
• Molecular Weight: 344.3618
• Product Categories: Amino Acids & Derivatives;Chiral Reagents;Amino Acids & Derivatives, Chiral Reagents
• Mol File: 337368-14-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 73-75 °C(Solv: ethyl acetate (141-78-6))
• Appearance: /
• Density: 1.268g/cm³
• Refractive Index: 1.585
• Solubility: Acetone, Chloroform, Dichloromethane
• PKA: 12.72±0.46(Predicted)
• CAS DataBase Reference: 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine(337368-14-6)
• EPA Substance Registry System: 3-[(Benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine(337368-14-6)

Safety Data

• Hazardous Substances Data: 337368-14-6(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

InChI:InChI=1/C18H20N2O5/c21-17(22)16(11-19-25-13-15-9-5-2-6-10-15)20-18(23)24-12-14-7-3-1-4-8-14/h1-10,16,19H,11-13H2,(H,20,23)(H,21,22)/t16-/m0/s1

Upstream product

• 622-33-3 N-benzyloxyamine 
• 26048-94-2 (S)-{2-[(phenylmethyloxy)amino]-1-(hydroxymethyl)-2-oxoethyl}carbamic acid phenylmethyl ester 
• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 
• 71404-99-4 (S)-[1-(phenylmethyloxy)-2-oxo-3-azetidinyl]carbamic acid phenylmethyl ester 

Downstream Products

• 832090-73-0 (S)-3-[nitroso(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine 
• 1482-97-9 L-α,β-diaminopropionic acid dihydrochloride 
• 832090-75-2 (S)-3-[(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine phenylmethyl ester 

Relevant articles and documents

An improved stereoselective synthesis of L-alanosine

An improved, stereoselective synthesis of the natural, non-proteogenic amino acid L-alanosine has been developed, starting from the readily available and cheap substrate L-serine, in six steps and 49% overall yield. The process is very efficient, is suitable for large-scale production, and affords L-alanosine with properties comparable with those of the natural substance. In addition, the structural assignment concerning some previously reported synthetic alkylated derivatives of the natural amino acid has been definitively confirmed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.