337375-99-2Relevant articles and documents
Progress toward the total synthesis of saudin: Development of a tandem Stille-oxa-electrocyclization reaction
Tambar, Uttam K.,Kano, Taichi,Stoltz, Brian M.
, p. 2413 - 2416 (2005)
(Chemical Equation Presented) A diastereoselective tandem Stille-oxa-electrocyclization reaction provides access to the core of the diterpenoid natural product saudin. Additionally, this new reaction sequence was extended to the convergent preparation of
INDOLE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)
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Paragraph 00234; 00316; 00778; 00781, (2021/10/11)
Indole derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD).
Convergent and diastereoselective synthesis of the polycyclic pyran core of saudin
Tambar, Uttam K.,Kano, Taichi,Zepernick, John F.,Stoltz, Brian M.
, p. 8357 - 8364 (2007/10/03)
The natural product saudin was found to induce hypoglycemia in mice and, therefore, could be an appealing lead structure for the development of new agents to treat diabetes. A diastereoselective tandem Stilleoxa- electrocyclization reaction has been devel