33738-48-6

Basic information

• Product Name: 4-METHYL-1-NAPHTHALDEHYDE
• Synonyms: 4-METHYL-1-NAPHTHALDEHYDE;4-Methyl-1-naphthaldehyde 97%;4-Methyl-1-phthaldehyde, 98%
• CAS NO: 33738-48-6
• Molecular Formula: C₁₂H₁₀O
• Molecular Weight: 170.21
• Product Categories: C10 to C21;Aldehydes;Carbonyl Compounds;Building Blocks;C10-C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 33738-48-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 32-36 °C(lit.)
• Boiling Point: 259.85°C (rough estimate)
• Flash Point: >230 °F
• Appearance: solid
• Density: 1.1252
• Vapor Pressure: 0.00037mmHg at 25°C
• Refractive Index: 1.6188 (estimate)
• CAS DataBase Reference: 4-METHYL-1-NAPHTHALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-1-NAPHTHALDEHYDE(33738-48-6)
• EPA Substance Registry System: 4-METHYL-1-NAPHTHALDEHYDE(33738-48-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 33738-48-6(Hazardous Substances Data)

Usage

Uses

4-Methyl-1-naphthaldehyde may be used in the synthesis of methyl 2-phenyl-3-( 4-methyl-1-naphthyl)propenoate and (Z/E)-2-amino-4,6-dimethyl-5-[(4-methyl-1-naphthyl)methylene]-5H-cyclopenta[b]pyridine-3,7-dicarbonitrile.

General Description

4-Methyl-1-naphthaldehyde is a monoaldehyde. It is obtained along with 1-methyl-2-naphthaldehyde from 1-methylnaphthalene, via formylation.

InChI:InChI=1/C12H10O/c1-9-6-7-10(8-13)12-5-3-2-4-11(9)12/h2-8H,1H3

Upstream product

• 571-58-4 1,4-dimethylnaphthalene 
• 141-82-2 malonic acid 
• 90-12-0 1-Methylnaphthalene 
• 1493-02-3 formyl fluoride 
• 201230-82-2 carbon monoxide 

Downstream Products

• 116672-26-5 (4-methylnaphthalen-1-yl)(phenyl)methanone 
• 10240-08-1 4-methyl-1-naphthol 
• 901273-15-2 N-(benzyloxycarbonyl)-β-(1-{4-[2',2'-bis(tert-butoxycarbonyl)vinyl]}naphthyl)-L-alanine 
• 901273-08-3 methyl (Z)-2-(benzyloxycarbonylamino)-3-{4-[2',2'-bis(tert-butoxycarbonyl)vinyl]}naphthylacrylate 
• 901273-11-8 methyl N-(benzyloxycarbonyl)-β-(1-{4-[2',2'-bis(tert-butoxycarbonyl)]vinyl}naphthyl)-L-alaninate 
• 104306-71-0 4-Methyl-1-naphthaldehyd-2,4-dinitrophenylhydrazon 
• 4488-40-8 4-Methyl-1-naphthoic acid 

Relevant articles and documents

Controlled photochemical release of nitric oxide from O2-naphthylmethyl- and O2-naphthylallyl-substituted diazeniumdiolates

The photochemistry of O2-naphthylmethyl- and O2-naphthylallyl-substituted diazeniumdiolates has been investigated. Electron-donating methoxy group substitution is shown to have a significant effect on the observed photochemistry, with the appropriate substitution pattern resulting in efficient diazeniumdiolate photorelease. Observed nitric oxide release rates from these photoprecursors are consistent with those expected for normal thermal dissociation of the diazeniumdiolate in aqueous solutions and show the same pH dependence. Copyright

The influence of aromatic compound protonation on the regioselectivity of Gattermann-Koch formylation

The regioselectivity of the Gattermann-Koch formylation is influenced by the protonation of aromatic compounds under a solvent-cage-like atmosphere.

Manganese(III)-Mediated Formylation of Aromatic Compounds in the Presence of Malonic Acid

The reaction of naphthlenes with malonic acid in the presence of manganese(III) acetate gives naphthalenecarbaldehydes and naphthalenecarboxylic acids.Similar reactions of anthracene, pyrene, and methoxybenzenes also yield formylated and carboxylated products.It was found that the formyl group introduced to the aromatic ring was not derived from carboxymethyl radical generated directly by the thermolysis of manganese(III) acetate, but from a dicarboxymethyl radical formed by the interaction of malonic acid and manganese(III) acetate.In addition, it was also found that the dicarboxymethyl radicals attacked the position of the highest electron density on the aromatic ring and that this formylation was effective when the ionization potential of the aromatic copound was lower than 7.8 eV.