33742-69-7Relevant articles and documents
Synthesis of 2-substituted 3-ethyl-3H-imidazo[4,5-b]pyridines catalyzed by Al3+-exchanged K10 clay as solid acids
Suresh, Dhanusu,Dhakshinamoorthy, Amarajothi,Kanagaraj, Kuppusamy,Pitchumani, Kasi
, p. 6479 - 6484 (2013)
A series of imidazopyridine derivatives have been synthesized efficiently via intramolecular cyclization in excellent yields using Al3+- exchanged on K10 montmorillonite clay (Al3+-K10 clay) as a reusable heterogeneous catalyst. To the best of our knowledge, this is the first report to utilize Al3+-K10 as a catalyst for imidazopyridine synthesis. Many functional groups are tolerated during the synthesis of targeted compounds. The catalyst is reused at least five times with a slight decrease in the yield. This catalyst is environmentally benign, cost-effective, and also provides other advantages such as nontoxicity, operational/experimental simplicity, and mild reaction conditions.
METALLOENZYME INHIBITOR COMPOUNDS
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Paragraph 0549; 0550; 0551; 0552, (2018/07/29)
Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
Design, Synthesis, and Fungicidal Activity of Novel Imidazo[4,5-b]pyridine Derivatives
Liu, Minhua,Quan, Chunsheng,Dang, Mingming,Ren, Yeguo,Ren, Jianwei,Xiang, Jun,Liu, Xingping,He, Lian,Liu, Weidong,Liu, Aiping
, p. 2061 - 2068 (2018/07/31)
A series of novel imidazo[4,5-b]pyridine derivatives were designed and synthesized. The structures of all the newly synthesized compounds were identified by spectroscopic data NMR, MS, and elemental analysis. Bioassay showed that the compounds exhibited potent fungicidal activities against Erysiphe graminis, Puccinia polysora, and so forth. Particularly, 2-chloro-5-((5-methoxy-2-(2-(trifluoromethyl)phenyl)-3H-imidazo[4,5-b]pyridin-3-yl)methyl)thiazole (9b) displayed fungicidal potency against P.?polysora. Its EC50 value: 4.00?mg/L is comparable with that of tebuconazole. The structure–activity relationship for the target compounds is discussed.