33748-47-9

Upstream product

• 49597-68-4 (6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester; hydrochloride 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 52681-36-4 diphenylmethyl (6R,7R)-7-isocyano-3-methylceph-3-em-4-carboxylate 
• 98376-17-1 diphenylmethyl(1S,6R,7S)-7-formamido-7-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)ceph-3-em-4-carboxylate-1-oxide 
• 98376-18-2 diphenylmethyl(1R,6R,7S)-7-formamido-7-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)ceph-3-em-4-carboxylate-1-oxide 
• 98376-14-8 diphenylmethyl(1S,6R,7S)-3-bromomethyl-7-formamido-7-methoxyceph-3-em-4-carboxylate-1-oxide 
• 98376-15-9 diphenylmethyl(1R,6R,7S)-3-bromomethyl-7-formamido-7-methoxyceph-3-em-4-carboxylate-1-oxide 
• 98393-50-1 diphenylmethyl(1S,6R,7S)-7-formamido-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide 
• 98376-08-0 diphenylmethyl(1R,6R,7S)-7-formamido-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide 
• 98376-09-1 diphenylmethyl(1S,6R,7S)-7-amino-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide hydrochloride 
• 98376-10-4 diphenylmethyl(1R,6R,7S)-7-amino-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide hydrochloride 
• 98376-16-0 diphenylmethyl(1S,6R,7S)-7-amino-3-bromomethyl-7-methoxyceph-3-em-4-carboxylate-1-oxide hydrobromide 
• 98376-21-7 diphenylmethyl(1S,6R,7S)-7-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)-7-(thien-2-yl)acetamidoceph-3-em-4-carboxylate-1-oxide 
• 64551-27-5 diphenylmethyl(6R,7S)-7-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)-7-(thien-2-yl)acetamidoceph-3-em-4-carboxylate 
• 98376-19-3 diphenylmethyl(6R,7S)-7-formamidoceph-7-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)ceph-3-em-4-carboxylate 
• 98376-20-6 diphenylmethyl(1S,6R,7S)-3-bromomethyl-7-methoxy-7-(thien-2-yl)acetamidoceph-3-em-4-carboxylate-1-oxide 

Relevant academic research and scientific papers

SYNTHESIS OF FUNCTIONALISED CEPHALOSPORINS. DIPHENYLMETHYL(1S,6R,7S)-3-BROMOMETHYL-7-FORMAMIDO-7-METHOXYCEPH-3-EM-4-CARBOXYLATE-1-OXIDE : A USEFUL INTERMEDIATE IN THE PREPARATION OF 7α-METHOXYCEPHALOSPORINS

The N-formamido cephalosporins 4a and 4b undergo direct methoxylation at the 7α-position to give the 7α-methoxy derivatives 5a and 5b.These were converted to other 7β-acylamido compounds by the sequence : oxidation, deformylation, acylation and reduction.