98376-07-9

Upstream product

• 67-56-1 methanol 
• 33748-47-9 diphenylmethyl(6R,7R)-7-formamido-3-methylceph-3-em-4-carboxylate 
• 49597-68-4 (6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester; hydrochloride 

Downstream Products

• 98376-08-0 diphenylmethyl(1R,6R,7S)-7-formamido-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide 
• 98393-50-1 diphenylmethyl(1S,6R,7S)-7-formamido-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide 
• 41968-39-2 diphenylmethyl(6R,7S)-7-methoxy-3-methyl-7-phenyl-acetamidoceph-3-em-4-carboxylate 
• 98376-11-5 (5S,6R,7S)-7-Methoxy-3-methyl-5,8-dioxo-7-phenylacetylamino-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 98376-10-4 diphenylmethyl(1R,6R,7S)-7-amino-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide hydrochloride 
• 98376-09-1 diphenylmethyl(1S,6R,7S)-7-amino-7-methoxy-3-methylceph-3-em-4-carboxylate-1-oxide hydrochloride 

Relevant academic research and scientific papers

SYNTHESIS OF FUNCTIONALISED CEPHALOSPORINS. DIPHENYLMETHYL(1S,6R,7S)-3-BROMOMETHYL-7-FORMAMIDO-7-METHOXYCEPH-3-EM-4-CARBOXYLATE-1-OXIDE : A USEFUL INTERMEDIATE IN THE PREPARATION OF 7α-METHOXYCEPHALOSPORINS

The N-formamido cephalosporins 4a and 4b undergo direct methoxylation at the 7α-position to give the 7α-methoxy derivatives 5a and 5b.These were converted to other 7β-acylamido compounds by the sequence : oxidation, deformylation, acylation and reduction.