337512-19-3Relevant academic research and scientific papers
Efficient synthesis of 3-aroylcinnolines from aryl methyl ketones
Al-Awadi, Nouria A,Elnagdi, Mohamed Hilmy,Ibrahim, Yehia A,Kaul, Kamini,Kumar, Ajith
, p. 1609 - 1614 (2007/10/03)
An efficient synthesis of 3-aroylcinnolines starting from the appropriate aryl methyl ketones is described. The latter were converted in two steps to the corresponding 3-oxo-3-aryl-2-arylhydrazonopropanals, which upon acid catalyzed cyclization in conc. s
Gas-phase pyrolysis in organic synthesis. Part 3: Novel cyclization of 2-arylhydrazonopropanals into cinnolines
Kumar, Ajith,Al-Awadi, Nouria A.,Elnagdi, Mohamed H.,Ibrahim, Yehia A.,Kaul, Kamini
, p. 402 - 406 (2007/10/03)
3-oxo-3-aryl-2-arylhydrazonopropanals (1) have been converted under thermal gas-phase conditions cleanly into cinnolines (2). A plausible mechanism is suggested to account for this transformation based on the kinetics and products of reaction.
