33757-36-7

Basic information

• Product Name: (4-methylphenyl)[4-(trifluoromethyl)phenyl]methanol
• Synonyms: (4-methylphenyl)[4-(trifluoromethyl)phenyl]methanol
• CAS NO: 33757-36-7
• Molecular Formula: C₁₅H₁₃F₃O
• Molecular Weight: 266.2583296
• Mol File: 33757-36-7.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-methylphenyl)[4-(trifluoromethyl)phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methylphenyl)[4-(trifluoromethyl)phenyl]methanol(33757-36-7)
• EPA Substance Registry System: (4-methylphenyl)[4-(trifluoromethyl)phenyl]methanol(33757-36-7)

Safety Data

• Hazardous Substances Data: 33757-36-7(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 104-87-0 4-methyl-benzaldehyde 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 34328-30-8 4-trifluoromethyl-4′-methylbenzophenone 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 455-13-0 4-Iodobenzotrifluoride 
• 455-18-5 4-CF₃C₆H₄CN 
• 4463-41-6 2-(p-tolyl)-1,3,2-dioxaborinane 

Downstream Products

• 170789-13-6 1-methyl-4-(4-(trifluoromethyl)benzyl)benzene 
• 34328-30-8 4-trifluoromethyl-4′-methylbenzophenone 
• 87901-58-4 C₁₅H₁₂F₃⁽¹⁺⁾ 
• 32045-08-2 Dimethyl-{2-[p-tolyl-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-amine 

Relevant articles and documents

Nickel Catalyzed Intermolecular Carbonyl Addition of Aryl Halide

In this study, we develop a nickel-catalyzed carbonyl arylation reaction employing aldehydes with aryl and allyl halides. Various aryl, α,β-unsaturated aldehyde and aliphatic aldehydes can be converted into their corresponding secondary alcohols in moderate-to-high yields. In addition, we extended this approach to develop an asymmetric reductive coupling reaction that combines nickel salts with chiral bisoxazoline ligands to give secondary alcohols with moderate enantioselectivity.

Co(III)-Catalyzed Synthesis of Quinazolines via C-H Activation of N-Sulfinylimines and Benzimidates

C-H activation of arenes has been established as an important strategy for heterocycle synthesis via annulations between arenes and unsaturated coupling partners. However, nitriles failed to act as such a coupling partner. Dioxazolones have been employed as a synthon of nitriles, and subsequent coupling with arenes such as N-sulfinylimines and benzimidates bearing a functionalizable directing group provided facile access to two classes of quinazolines under Co(III)-catalysis.

Alkynes as activators in the nickel-catalysed addition of organoboronates to aldehydes

Alkynes act not as substrates but as co-catalysts in the presence of a nickel catalyst, an organoboronate and an aldehyde to promote the addition reaction between the substrates in combination with H2O. The Royal Society of Chemistry 2005.