337902-35-9

Upstream product

• 337902-75-7 4-(4-Fluorophenyl)-2-(1-ethoxycarbonylpiperidin-4-yl)-5-(2-fluoro-4-pyridinyl)thiazole 
• 302839-10-7 2-bromo-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone 
• 337902-71-3 4-thiocarbamoylpiperidine-1-carboxylic acid ethyl ester 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 337902-76-8 4-{4-(4-Fluoro-phenyl)-5-[2-((S)-1-phenyl-ethylamino)-pyridin-4-yl]-thiazol-2-yl}-piperidine-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis

A library of trisubstituted oxazoles, thiazoles, imidazoles (1,2,4- and 2,4,5-substituted) and imidazo[1,2-b]pyridines was prepared and evaluated in vitro as p38α inhibitors and in vivo in several models of rheumatoid arthritis. Four structures - 32, 37,