337974-47-7

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 205816-66-6 4-[(4'-methylphenyl)sulfonyl]-1-(triphenyphosphoranylidene)-2-butanone 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 205816-67-7 1-bromo-4-[(4'-methylphenyl)sulfonyl]-2-butanone 
• 61476-94-6 4-[(4'-methylphenyl)sulfonyl]-2-butanone 

Downstream Products

• 40179-50-8 (2S)-N-4'-nitrobenzoyl-2-(3-pyridyl)-4-piperidine 
• 494-52-0 Anabasine 
• 337974-58-0 (2S)-N-[(1S)-1-phenylethyl]-2-(3-pyridyl)-4-piperidine 
• 337974-57-9 (S)-8-((S)-1-Phenyl-ethyl)-7-pyridin-3-yl-1,4-dithia-8-aza-spiro[4.5]decane 

Relevant academic research and scientific papers

4-[(4'-Methylphenyl)sulfonyl]-1-(trophenylphosphoranylidene)-2-butanone as a New Four-Carbon Synthon for Substituted Divinyl Ketones

The title compound and the corresponding anion have been conveniently used as precursors of substituted divinylketones in both carbo- and heterocyclization reactions in one-pot, three-step sequences leading to a wide variety of substituted carbo- and heterocyclic ring systems, as well as to multifunctionalized linear carbon frameworks. The compounds generated through the use of this multi-coupling reagent represent useful synthons for the construction of natural compounds including (+/-)-epibatidine, (-)-anabasine and (+/-)-pyrenophorin.

4-[(4-methylphenyl)sulfonyl]-1-(triphenylphosphoranylidene)-2- butanone and its dianion as versatile tools in organic synthesis

The title compound and the corresponding dianion have been used as convenient precursors for substituted divinyl ketones in both carbo- and heterocyclization reactions in a one-pot three-step sequence leading to substituted carbo- and heterocyclic ring systems and for the construction of the 4-keto-2-alkenoate subunit, a common structural feature of a variety of natural compounds, respectively.