337974-95-5Relevant academic research and scientific papers
Enantioselective synthesis of the ester side chain of homoharringtonine
Keller, Laurent,Dumas, Francoise,D'Angelo, Jean
, p. 2488 - 2497 (2007/10/03)
Details of the synthesis of the methyl ester of the side chain of homoharringtonine, a natural product with antileukemic properties, are reported below. The key tactical element involved a Michael addition between the known chiral imine 4 and 2-acetoxyacr
