33817-97-9Relevant academic research and scientific papers
Regiocontrol in the palladium-catalyzed hydrophosphinylation of terminal alkynes
Belabassi, Yamina,Bravo-Altamirano, Karla,Montchamp, Jean-Luc
, p. 106 - 111 (2011)
The regioselectivity of the palladium-catalyzed hydrophosphinylation of terminal alkynes was investigated. Complementary conditions to achieve the predominant formation of either the linear or the branched alkenyl-H-phosphinate products were identified. W
NiCl2-catalyzed hydrophosphinylation
Ribiere, Patrice,Bravo-Altamirano, Karla,Antczak, Monika I.,Hawkins, Jennifer D.,Montchamp, Jean-Luc
, p. 4064 - 4072 (2005)
A new nickel-based catalytic system has been developed for phosphorus-carbon bond formation. The addition of alkyl phosphinates to alkynes is catalyzed by nickel chloride in the absence of added ligand. The reaction generally proceeds in high yields, even with internal alkynes, which were poor substrates in our previously reported palladium-catalyzed hydrophosphinylation of alkyl phosphinates. The method is useful for the preparation of H-phosphinate esters and their derivatives. The one-pot synthesis of various important organophosphorus compounds is also demonstrated. The reaction can be conducted with microwave heating.
Synthesis of Z-alkenyl phosphorus compounds through hydroalumination and carbocupration of alkynyl precursors
Ortial, Stephanie,Montchamp, Jean-Luc
, p. 3134 - 3137 (2011/07/31)
The stereocontrolled synthesis of Z-alkenylphosphine-borane complexes is easily accomplished via the hydroalumination or carbocupration of alkynyl precursors. Z/E ratios are generally higher than 95/5. These reactions are stereocomplementary to our olefination approach.
