338454-32-3

Usage

Structure

Benzene ring with a bromine atom at the 4th position
Methyl group at the 2nd position
Benzyloxy group attached to the 1st position of the benzene ring

Physical state

Pale yellow to brown colored liquid

Applications

Synthesis of pharmaceutical and agrochemical products
Building block for the preparation of a wide range of organic compounds

Upstream product

• 2362-12-1 4-Bromo-2-methylphenol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 1445853-53-1 N-hydroxy-2-(2-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)oxazol-4-yl)acetamide 
• 1445853-88-2 ethyl 2-(2-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)oxazol-4-yl)acetate 
• 1445853-85-9 ethyl 2-(2-(3-(4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl)pentan-3-yl)oxazol-4-yl)acetate 
• 1445853-82-6 ethyl 2-(2-(3-(4-hydroxy-3-methylphenyl)pentan-3-yl)oxazol-4-yl)acetate 
• 1445853-79-1 ethyl 2-(2-(3-(4-(benzyloxy)-3-methylphenyl)pentan-3-yl)oxazol-4-yl)acetate 
• 1445853-78-0 2-(4-(benzyloxy)-3-methylphenyl)-2-ethylbutanamide 
• 895128-27-5 2-(4-(benzyloxy)-3-methylphenyl)-2-ethylbutanoic acid 
• 895128-28-6 2-(4-benzyloxy-3-methyl-phenyl)-2-ethyl-butyryl chloride 
• 895128-26-4 methyl 2-(4-(benzyloxy)-3-methylphenyl)-2-ethylbutanoate 
• 1257078-80-0 4-benzyloxy-3-methylphenylboronic acid pinacol ester 
• 309947-26-0 4-(4'-Benzyloxy-3'-methylbiphenyl-4-yloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 338454-30-1 [4-(benzyloxy)-3-methylphenyl]boronic acid 

Relevant academic research and scientific papers

TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF

A tetrazolinone compound represented by formula (1): wherein Q represents a 6-membered aromatic heterocyclic group optionally having one or more atoms or groups selected from Group P1, provided that a heteroatom constituting the heterocyclic gr

1,2,3,4-TETRAHYDROISOQUINOLINE COMPOUNDS AND COMPOSITIONS AS SELECTIVE ESTROGEN RECEPTOR ANTAGONISTS AND DEGRADERS

The present invention relates to compounds of formula (I) in which n, R1, R2, R3, R4and R5 are as defined in the claims; capable of being both potent antagonists and degraders of estrogen receptors. Also described is a process for the preparation of compounds of the invention, and the invention further provides pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with aberrant estrogen receptor activity.

BIS-(ARYL/HETEROARYL)-METHYLENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND THEIR USE FOR TREATING CANCER

The present disclosure relates to novel bis-(aryl/heteroaryl)-methylene compounds of formula (I) having vitamin D receptor agonist and histone deacetylase (HDAC) inhibitory efficacy as well as to methods for reducing or inhibiting the proliferation of can

CONTINUOUS ARYCYCLIC COMPOUND

This is to provide a continuous arycyclic compound having a DGAT1 inhibitory activity, and useful for prophylaxis and/or treatment of obesity or hyperlipidemia caused by obesity, hypertriglyceridemia, lipid metabolism disorder, fatty liver, hypertension,

PYRIMIDINE INHIBITORS OF KINASE ACTIVITY

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-IR.

PESTICIDAL SUBSTITUTED PHENYLETHERS

The invention relates to the use of phenylether derivatives of formula (I), to compositions thereof for the control of pests, including arthropods and helminths.

Substituted 5-benzyl-2,4-diaminopyrimidines

The invention relates to substituted 5-benzyl-2,4-diaminopyrimidines of general formula (A) wherein R1is C2-C3 alkyl an R2is heterocyclyl, phenyl or naphthyl, bonded by one of its C-atoms and R3is C2-C6 alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, heterocyclylalkyl, alkylsulfonyl, cycloalkylsulfonyl, cycloalkylalkylsulfamoyl, heterocyclysylfonyl, heterocyclylalkylsulfonyl or dialkylsulfamoyl; wherein alkyl, cycloalkyl and alyenyl can carry up to 6 carbon atoms alone or in compositions and can carry up to 6 ring members heterocyclically, alone, or in compositions and the groups R2and R3can be substituted; and to acid addition salts of compounds. The invention also relates to a method for producing the above 5-benzyl-2,4-diaminopyrimidines, to the intermediate. products that are produced, to corresponding medicaments and to the use of 5-benzyl-2,4-diaminopyrimidines as medicinal preparations. The products have antibiotic properties and are useful for combating or preventing infectious diseases.

Thermotropic and lyotropic liquid crystalline phases of rigid aromatic amphiphiles

Rodlike amphiphilic molecules that contain exclusively aromatic building-blocks and no flexible alkyl chains have been synthesized and their mesomorphic properties investigated. These novel compounds bear diol head groups of different size (2,3-dihydroxypropyloxy or 5,6-dihydroxy-3-oxahexyloxy groups) at one end of a biphenyl unit, various aromatic segments (benzyloxy, 4-, 3-, or 2-methylbenzyloxy, phenoxy groups) at the other, and additional methyl substituents in different positions. They were synthesized by using Suzuki cross-coupling reactions as the key steps. Their thermotropic mesomorphism was investigated by means of polarized light optical microscopy, differential scanning calorimetry, and, for enantiotropic phases, by X-ray scattering. The liquid crystallinity of this class of compounds is influenced by protic solvents, such as water and glycerol. Dependent on the temperature and the solvent content, different SA phases were found. Several mesophases resulting from the frustration of these layer structures (e.g., different columnar phases, optical isotropic mesophases, and nematic phases) were also present. The smectic phases have different degrees of intercalation (SAd, SA2). The columnar phases are supposed to be ribbon structures that result from the collapse of the smectic layers. They occur in some pure compounds or they are induced upon the addition of protic solvents. The particular phase sequences of the different compounds depend mainly on the position of the methyl substituents at the biphenyl cores and are largely determined by the degree of intercalation of the aromatic cores.