33856-02-9

Basic information

• Product Name: 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-one
• Synonyms: 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-one;3-[2-(phenylamino)-1,3-thiazol-4-yl]-2H-chromen-2-one
• CAS NO: 33856-02-9
• Molecular Formula: C₁₈H₁₂N₂O₂S
• Molecular Weight: 320.36508
• Mol File: 33856-02-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-one(33856-02-9)
• EPA Substance Registry System: 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-one(33856-02-9)

Safety Data

• Hazardous Substances Data: 33856-02-9(Hazardous Substances Data)

Upstream product

• 3949-36-8 3-acetylcoumarin 
• 103-85-5 monophenylthiourea 
• 90-02-8 salicylaldehyde 
• 453524-57-7 ethyl-2-(2-(phenylamino)thiazol-4-yl)acetate 
• 141099-74-3 3-(2-thiocyanatoacetyl)-2H-1-benzopyran-2-one 
• 62-53-3 aniline 
• 29310-88-1 3-bromoacetylcoumarin 

Downstream Products

• 33856-10-9 3-(2-anilino-5-bromo-thiazol-4-yl)-chromen-2-one 
• 108222-34-0 3-[2-(N-acetyl-anilino)-thiazol-4-yl]-coumarin 
• 936096-68-3 2-phenylamino-4-(coumarin-3-yl)-5-formylthiazole 

Relevant articles and documents

An expedient one-pot tandem method for the synthesis of 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-ones under green conditions

This paper describes a facile pathway for the one-pot three-component synthesis of 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-ones starting from ethyl-4-chloroacetoacetate by treating it with equimolar amounts of various phenylthioureas independently re

Green approach: An efficient synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles in aqueous medium under ultrasonic irradiation

An efficient and rapid procedure for the synthesis of 2,4-disubstituted-1,3-thiazoles and selenazoles has been described by the reaction of α-bromoketones with thiourea, phenylthiourea and selenourea at ambient temperature in aqueous medium under ultrasonic irradiation. Analytically pure products were formed within 10-60 s in excellent yields. The advantageous features of this non-conventional methodology over conventional methods are the operational simplicity, easy handling, yield-enhancing, time-reducing, mild reaction conditions and no by-product production.

One pot synthesis of 3-[2-(arylamino)thiazol-4-yl]coumarins in a three-component synthesis and a catalyst and solvent-free synthesis on grinding

An efficient synthesis of 3-[2-(arylamino)thiazol-4-yl]coumarins in excellent yields are described. Reaction of 3-(2-bromoacetyl)coumarin with potassium thiocyanate and arylamines, in alcohol resulted in the formation of title compounds in one pot. The sa