33858-36-5

Usage

Uses

Used in Organic Chemistry and Materials Science:
2,6-di(benzo(d)oxazol-2-yl)pyridine is used as a fluorescent dye and a component of light-emitting materials due to its unique properties. Its role in these applications is crucial for the development of advanced materials with specific optical and electronic characteristics.
Used in Organic Electronics:
In the field of organic electronics, 2,6-di(benzo(d)oxazol-2-yl)pyridine is utilized as a key component in the creation of materials with tailored electronic properties. Its incorporation into organic electronic devices can enhance performance and functionality.
Used in Optoelectronic Devices:
2,6-di(benzo(d)oxazol-2-yl)pyridine is employed in the development of optoelectronic devices, where its light-emitting and fluorescent properties contribute to improved device performance and efficiency.
Used in Biological Imaging:
2，6-di（benzo（d）oxazol-2-yl）pyridine is also used in biological imaging as a fluorescent marker, allowing for the visualization and tracking of biological processes at the molecular level.
Used in Chemical and Biological Sensing Applications:
2,6-di(benzo(d)oxazol-2-yl)pyridine has been studied for its potential as a sensory and detection agent, where its unique properties can be harnessed for the sensitive and selective detection of chemical and biological species.

InChI:InChI=1/C19H11N3O2/c1-3-10-16-12(6-1)21-18(23-16)14-8-5-9-15(20-14)19-22-13-7-2-4-11-17(13)24-19/h1-11H

Upstream product

• 499-83-2 Pyridine-2,6-dicarboxylic acid 
• 95-55-6 2-amino-phenol 
• 96308-77-9 N,N'-bis(2-hydroxyphenyl)-pyridine-2,6-dicarboxamide 
• 3739-94-4 2,6-Pyridinedicarbonyl dichloride 
• 1643-19-2 tetrabutylammomium bromide 

Relevant academic research and scientific papers

Selective sensing of Fe3+ based on fluorescence quenching by 2,6-bis(benzoxazolyl)pyridine with β-cyclodextrin in neutral aqueous solution

A selective and sensitive fluorescent chemosensor (BBOZP-CD) for Fe3+ was composed of water-soluble β-cyclodextrins and 2,6-bis(benzoxazolyl)pyridine which was synthesized through the reaction of 2,6-pyridinedicarboxylic acid and o-aminophenol catalyzed by polyphosphoric acid under microwave irradiation. The chemosensor BBOZP-CD for metal ions were carefully investigated by fluorescent quenching in present of metal ions. The result showed BBOZP-CD chemosensor was remarkable fluorescence quenching and a highly selectivity and sensitivity for Fe3+ in neutral aqueous solution, and the other common metal ions did not notably disturb the detection of Fe3+. Additionally, the effect of pH to the chemosensor for Fe3+ was also studied. The result indicated the respond signals of BBOZP-CD to Fe3+ was stable and hardly influenced while the pH value was greater than 3.6.

Palladium(II) complexes of tridentate bis(benzazole) ligands: Structural, substitution kinetics, DNA interactions and cytotoxicity studies

Reactions of 2,6-bis(benzimidazol-2-yl)pyridine (L1), 2,6-bis(benzoxazol-2-yl)pyridine (L2), and 2,6-bis(benzothiazol-2-yl)pyridine (L3) with [Pd(NCMe)2Cl2] in the presence of NaBF4 afforded the corresponding Pd(II) complexes, [Pd(L1)Cl]BF4, PdL1; [Pd(L2)Cl]BF4, PdL2; [Pd(L3)Cl]BF4, PdL3; respectively, while reaction of bis[(1H-benzimidazol-2-yl)methyl]amine (L4) with [Pd(NCMe)2Cl2] afforded complex [Pd(L4)Cl]Cl, PdL4. Characterisation of the complexes was accomplished using NMR, IR, MS, elemental analyses and single crystal X-ray crystallography. Ligand substitution kinetics of these complexes by biological nucleophiles thiourea (Tu), L-methionine (L-Met) and guanosine 5′-diphosphate disodium salt (5-GMP) were examined under pseudo-first order conditions. The reactivity of the complexes decreased in the order: PdL1 > PdL2 > PdL3 > PdL4, ascribed to electronic effects. Density functional theory (DFT) supported this trend. Studies of interaction of the Pd(II) complexes with calf thymus DNA (CT-DNA) revealed strong binding affinities via intercalative binding mode. Molecular docking studies established associative non-covalent interactions between the Pd complexes and DNA. The in vitro cytotoxic activities of PdL1–PdL4 were assessed in cancer cell lines HeLa and MRC5-SV2 and a normal cell line MRC-5, using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. PdL1 exhibited cytotoxic potency and selectivity against HeLa cell that was comparable to cisplatin's. Complex PdL1, unlike cisplatin, did not significantly induce caspase-dependent apoptosis.

Polycyclic pyridines as potassium ion channel modulators

The present invention provides a genus of polycyclic pyridines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.

Separation of lanthanides and actinides(III) using tridentate benzimidazole, benzoxazole and benzothiazole ligands

The ability of new hydrophobic tridentate ligands based on 2,6-bis(benzimidazol-2-yl)pyridine, 2,6-bis(benzoxazol-2-yl)pyridine and 2,6-bis(benzothiazol-2-yl)pyridine to selectively extract americium(III) from europium(III) was measured. The most promisin

Models for Copper-Dioxygen Complexes: the Chemistry of Copper(II) with Some Planar Tridentate Nitrogen Ligands

The solution chemistry of Cu(II) with a series of five planar tridentate nitrogen ligands, 2,6-bis(benzimidazol-2-yl)pyridine (bzimpy, 1), 2,6-bis(1-methylbenzimidazol-2-yl)pyridine (mbzimpy, 2), 2,6-bis(benzothiazol-2-yl)pyridine (bzthpy, 3), 2,6-bis(benzoxazol-2-yl)pyridine (bzoxpy, 4), and 2,2',6',2"-terpyridyl (terpy, 5) is reported.Electronic and EPR spectra are consistent with the complexes 2+ having essentially tetragonal structure in solution, with the fourth coordination site in the plane of the ligand occupied by solvent. bzthpy and bzoxpy show smaller ligand-field splittings than bzimpy, mbzimpy, and terpy, and are easily decomplexed from the copper.Substitution of the coordinated solvent molecule in the plane of the ligand is observed with Cl- and OH- (provided that the ligand has no acidic protons) for all ligands except terpy.The reaction between 2+ and imidazole has been studied by potentiometric titration in MeCN/H2O 1:1 and shows strong binding of the imidazole in the plane (log K = 4.5 at 25 deg C), and also the formation of an imidazolate-bridged dinuclear species.

Eine einfache Methode zur Herstellung von Benzoxazolen

The preparation of benzoxazoles by a facile one-pot reaction is reported.The reaction of carboxylic acids with 2-chloro-N-methyl-Δ1-pyrrolinium chloride in an excess of N-methyl-2-pyrrolidone afforded carboxylic acid chlorides which were converted subsequently to their 2-hydroxyanilides by addition of 2-aminophenols.Cyclization of the 2-hydroxy-anilides at elevated temperatures furnished the benzoxazoles in high yield and purity.