33873-09-5 Usage
Uses
Used in Pharmaceutical Industry:
2,6-Difluoropyrazine is used as a key intermediate in the synthesis of pyrazolopyrimidines, which are compounds with potential antiviral properties. Specifically, these pyrazolopyrimidines may be effective against respiratory syncytial virus, a common cause of respiratory infections.
Additionally, 2,6-difluoropyrazine is utilized in the preparation of 2,6-diphenoxypyridine factor Xa inhibitors. These inhibitors are part of a class of anticoagulant drugs that target factor Xa, an enzyme involved in the blood clotting process. By inhibiting factor Xa, these drugs can help prevent the formation of blood clots, which is particularly important for individuals at risk of thrombotic events.
Check Digit Verification of cas no
The CAS Registry Mumber 33873-09-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,8,7 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 33873-09:
(7*3)+(6*3)+(5*8)+(4*7)+(3*3)+(2*0)+(1*9)=125
125 % 10 = 5
So 33873-09-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H2F2N2/c5-3-1-7-2-4(6)8-3/h1-2H
33873-09-5Relevant academic research and scientific papers
NUCLEOPHILIC FLUORINATION OF CHLORINATED N-HETEROCYCLES WITH TETRABUTYLPHOSPHONIUM HYDROGENDIFLUORIDE AND DIHYDROGENTRIFLUORIDE
Uchibori, Yukitaka,Umeno, Masayuki,Yoshioka, Hirosuke
, p. 1507 - 1510 (2007/10/02)
Fluorination of various chlorinated N-heterocycles with tetrabutylphosphonium hydrogendifluoride (1) or dihydrogentrifluoride (2) readilly proceeded in high yields under mild conditions.
