Welcome to LookChem.com Sign In|Join Free
  • or
7-(allyloxy)-3-(2,4,5-trimethoxyphenyl)-4H-chromen-4-one is a complex organic compound belonging to the class of flavonoids, specifically flavones. This molecule is characterized by a chromenone core, which is a type of flavonoid with a lactone ring. The compound features a 2,4,5-trimethoxyphenyl group attached at position 3, which contributes to its antioxidant properties due to the presence of electron-donating methoxy groups. Additionally, an allyl group is attached at position 7, which may influence the compound's reactivity and biological activity. This chemical structure is of interest in the field of natural products chemistry and pharmacology, as it may possess potential therapeutic applications, particularly in the areas of antioxidant and anti-inflammatory effects.

3389-28-4

Post Buying Request

3389-28-4 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

3389-28-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3389-28-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,8 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3389-28:
(6*3)+(5*3)+(4*8)+(3*9)+(2*2)+(1*8)=104
104 % 10 = 4
So 3389-28-4 is a valid CAS Registry Number.

3389-28-4Downstream Products

3389-28-4Relevant academic research and scientific papers

Synthesis, structure-activity relationships and biological evaluation of barbigerone analogues as anti-proliferative and anti-angiogenesis agents

Wang, Guangcheng,Wang, Fang,Cao, Dong,Liu, Yibin,Zhang, Ronghong,Ye, Haoyu,Li, Xiuxia,He, Lin,Yang, Zhuang,Ma, Liang,Peng, Aihua,Xiang, Mingli,Wei, Yuquan,Chen, Lijuan

, p. 3158 - 3163 (2014/06/24)

A series of barbigerone analogues (7a-7w, 13a-13x) were designed, synthesized and biologically evaluated for their anti-proliferative and anti-angiogenic activities. Among these compounds, compound 13a exhibited the most potent inhibitory effect on the proliferation of HUVECs, HepG2, A375, U251, B16, and HCT116 cells (IC50 = 3.80, 0.28, 1.58, 3.50, 1.09 and 0.68 μM, respectively). Compound 13a inhibited the angiogenesis in zebrafish embryo assay in a concentration-dependent manner. Furthermore, 13a also effectively inhibited the migration and capillary like tube formation of human umbilical vein endothelial cell in vitro. These results support the further investigation of this class of compounds as potential anti-proliferative and anti-angiogenesis agents.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 3389-28-4