3389-80-8Relevant academic research and scientific papers
Fe-promoted radical cyanomethylation/arylation of arylacrylamides to access oxindoles via cleavage of the sp3 C-H of acetonitrile and the sp2 C-H of the phenyl group
Pan, Changduo,Zhang, Honglin,Zhu, Chengjian
, p. 361 - 364 (2015)
Radical cyanomethylation/arylation of arylacrylamides to access oxindoles with acetonitrile as the radical precursor is described. This reaction involves dual C-H bond functionalization, including the sp3 C-H of acetonitrile and the sp2/s
Cascade arylalkylation of activated alkenes: Synthesis of chloro- and cyano-containing oxindoles
Li, Xueqin,Xu, Jian,Gao, Yuzhen,Fang, Hua,Tang, Guo,Zhao, Yufen
, p. 2621 - 2626 (2015/03/18)
The general method for the oxidative cyclization of arylacrylamides with dichloromethane or acetonitrile has been developed. The reactions described provide novel access to chloro- and cyano-containing oxindoles in good to moderate yields that allow the direct formation of a C-C bond and the construction of an oxindole ring in one reaction. The use of a cheap and easily prepared Mn(OAc)3 represents an added advantage of this method.
